1ZHB

Crystal Structure Of The Murine Class I Major Histocompatibility Complex Of H-2Db, B2-Microglobulin, and a 9-Residue Peptide Derived from rat dopamine beta-monooxigenase

Summary for 1ZHB

• Entry DOI: 10.2210/pdb1zhb/pdb
• Related: 1JUF 1N5A 1S7U
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, 9-mer peptide from Dopamine beta-monooxygenase, ... (4 entities in total)
• Functional Keywords: mhc, tcr-crossreactivity, self-ligand, autoimmunity, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887; Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen . Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type II membrane protein : Q05754
• Total number of polymer chains: 12
• Total formula weight: 179381.17

Authors

Sandalova, T.,Michaelsson, J.,Harris, R.A.,Odeberg, J.,Schneider, G.,Karre, K.,Achour, A. (deposition date: 2005-04-25, release date: 2005-06-14, Last modification date: 2023-10-25)

• Primary citation: Sandalova, T.,Michaelsson, J.,Harris, R.A.,Odeberg, J.,Schneider, G.,Karre, K.,Achour, A.; A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity; J.Biol.Chem., 280:27069-27075, 2005; PubMed: 15845547; DOI: 10.1074/jbc.M500927200

Experimental method

X-RAY DIFFRACTION (2.7 Å)