8HXY
 
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7K6Q
 | | Active state Dot1 bound to the H4K16ac nucleosome | | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. | | 登録日 | 2020-09-21 | | 公開日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Science, 371, 2021
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6RYR
 | | Nucleosome-CHD4 complex structure (single CHD4 copy) | | 分子名称: | Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | | 著者 | Farnung, L, Ochmann, M, Cramer, P. | | 登録日 | 2019-06-11 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
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7XFM
 | | Structure of nucleosome-AAG complex (A-53I, post-catalytic state) | | 分子名称: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | | 著者 | Zheng, L, Tsai, B, Gao, N. | | 登録日 | 2022-04-01 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
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7EA8
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7X3W
 | | Cryo-EM structure of ISW1-N1 nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (146-MER), ... | | 著者 | Lifei, L, Kangjing, C, Chen, Z. | | 登録日 | 2022-03-01 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the ISW1a complex bound to the dinucleosome.
Nat.Struct.Mol.Biol., 31, 2024
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3C1C
 | | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | | 分子名称: | Histone 2, H2bf, Histone H2A type 1, ... | | 著者 | Lu, X, Simon, M, Chodaparambil, J, Hansen, J, Shokat, K, Luger, K. | | 登録日 | 2008-01-22 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure.
Nat.Struct.Mol.Biol., 15, 2008
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3MGS
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7CRQ
 | | NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode) | | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | | 登録日 | 2020-08-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
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8ETV
 | | Class2 of the INO80-Hexasome complex | | 分子名称: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | | 登録日 | 2022-10-17 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
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4XUJ
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8G8G
 | | Interaction of H3 tail in LIN28B nucleosome with Oct4 | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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7UX9
 | | Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA) | | 分子名称: | ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... | | 著者 | Ipsaro, J.J, Adams, D.W, Joshua-Tor, L. | | 登録日 | 2022-05-05 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Cell, 186, 2023
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3KXB
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2FJ7
 | | Crystal structure of Nucleosome Core Particle Containing a Poly (dA.dT) Sequence Element | | 分子名称: | 147 bp DNA containing 16 bp poly dA element, 147 bp DNA containing 16 bp poly dT element, Histone H2B, ... | | 著者 | Bao, Y, White, C.L, Luger, K. | | 登録日 | 2005-12-31 | | 公開日 | 2006-09-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Nucleosome Core Particles Containing a Poly(dA.dT) Sequence Element Exhibit a Locally Distorted DNA Structure.
J.Mol.Biol., 361, 2006
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8SVF
 | | BAP1/ASXL1 bound to the H2AK119Ub Nucleosome | | 分子名称: | DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ... | | 著者 | Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J. | | 登録日 | 2023-05-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Sci Adv, 9, 2023
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7NKY
 | | RNA Polymerase II-Spt4/5-nucleosome-FACT structure | | 分子名称: | Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ... | | 著者 | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | | 登録日 | 2021-02-19 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
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7YRD
 | | histone methyltransferase | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | 著者 | Li, H, Wang, W.Y. | | 登録日 | 2022-08-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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7SSA
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7XPX
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8GPN
 | | Human menin in complex with H3K79Me2 nucleosome | | 分子名称: | DNA (177-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Lin, J, Yu, D, Lam, W.H, Dang, S, Zhai, Y, Li, X.D. | | 登録日 | 2022-08-26 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Menin "reads" H3K79me2 mark in a nucleosomal context.
Science, 379, 2023
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7K6P
 | | Active state Dot1 bound to the unacetylated H4 nucleosome | | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. | | 登録日 | 2020-09-21 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Science, 371, 2021
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6S01
 | | Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome | | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | | 著者 | Wang, H, Farnung, L, Dienemann, C, Cramer, P. | | 登録日 | 2019-06-13 | | 公開日 | 2019-12-18 | | 最終更新日 | 2020-01-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding.
Nat.Struct.Mol.Biol., 27, 2020
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7CRP
 | | NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (1:1 binding mode) | | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | | 登録日 | 2020-08-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
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6KIU
 | | Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) | | 分子名称: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | | 著者 | Huang, J, Xue, H, Yao, T. | | 登録日 | 2019-07-20 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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