7XPX

Cryo-EM structure of the histone methyltransferase SET8 bound to H4K20Ecx-nucleosome

Summary for 7XPX

• Entry DOI: 10.2210/pdb7xpx/pdb
• EMDB information: 33385
• Descriptor: Histone H3, Histone H4, Histone H2A, ... (8 entities in total)
• Functional Keywords: methyltransferase, nucleosome, nuclear protein-dna complex, nuclear protein/dna
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 11
• Total formula weight: 223406.61

Authors

Shi, L.X.,Zhou, Z. (deposition date: 2022-05-06, release date: 2022-06-01)

• Primary citation: Shi, L.,Huang, L.,Long, H.,Song, A.,Zhou, Z.; Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8.; Faseb J., 36:e22338-e22338, 2022; PubMed: 35532550; DOI: 10.1096/fj.202101821R

Experimental method

ELECTRON MICROSCOPY (3.2 Å)