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PDB: 465 件

8OOP
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CryoEM Structure INO80core Hexasome complex composite model state2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-07-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
4FWF
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Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ...
著者Zhang, Q, Chen, Z.
登録日2012-07-01
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
3AZL
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BU of 3azl by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H4K77Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AZF
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Crystal Structure of Human Nucleosome Core Particle Containing H3K79Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AZI
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BU of 3azi by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
6V3N
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BU of 6v3n by Molmil
Crystal structure of CDYL2 in complex with H3K27me3
分子名称: ACE-GLN-LEU-ALA-THR-LYS-ALA-ALA-ARG-M3L-SER-ALA-PRO-ALA-THR-TYR-NH2, Chromodomain Y-like protein 2, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2019-11-26
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
5HJB
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AF9 YEATS in complex with histone H3 Crotonylation at K9
分子名称: Protein AF-9, peptide of Histone H3.1
著者Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
登録日2016-01-12
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
3U5O
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Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-22)K9me3K14acK18ac histone peptide
分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2011-10-11
公開日2012-01-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
8OX1
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Structure of TRF1core in complex with telomeric nucleosome
分子名称: Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ...
著者Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D.
登録日2023-04-28
公開日2023-08-30
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
5GTC
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Crystal structure of complex between DMAP-SH conjugated with a Kaposi's sarcoma herpesvirus LANA peptide (5-15) and nucleosome core particle
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Arimura, Y, Kato, D, Suto, H, Kurumizaka, H, Kawashima, S.A, Yamatsugu, K, Kanai, M.
登録日2016-08-19
公開日2017-06-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Synthetic Posttranslational Modifications: Chemical Catalyst-Driven Regioselective Histone Acylation of Native Chromatin.
J. Am. Chem. Soc., 139, 2017
4FT4
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BU of 4ft4 by Molmil
crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH
分子名称: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE
著者Du, J, Patel, D.J.
登録日2012-06-27
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants.
Cell(Cambridge,Mass.), 151, 2012
3UIK
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BU of 3uik by Molmil
crystal structure of human Survivin mutant K62Y/H80W in complex with H3(1-10) peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3(1-10) peptide
著者Du, J, Patel, D.J.
登録日2011-11-04
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
5FB0
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Crystal Structure of a PHD finger bound to histone H3 T3ph peptide
分子名称: Nuclear autoantigen Sp-100, Peptide from Histone H3, ZINC ION
著者Li, H, Zhang, X.
登録日2015-12-13
公開日2016-05-04
最終更新日2016-06-22
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C
J.Biol.Chem., 291, 2016
5J9S
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ENL YEATS in complex with histone H3 acetylation at K27
分子名称: H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION
著者Li, Y, Li, H.
登録日2016-04-11
公開日2017-03-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
Nature, 543, 2017
8DK5
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Structure of 187bp LIN28b nucleosome with site 0 mutation
分子名称: DNA (187-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-07-02
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
2UXN
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BU of 2uxn by Molmil
Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation
分子名称: CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H.
登録日2007-03-28
公開日2007-05-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
5Z23
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Crystal structure of the nucleosome containing a chimeric histone H3/CENP-A CATD
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Arimura, Y, Tachiwana, H, Takagi, H.
登録日2017-12-28
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
4A0N
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Crystal structure of Survivin bound to the phosphorylated N-terminal tail of histone H3
分子名称: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, HISTONE H3 PEPTIDE, ZINC ION
著者Jeyaprakash, A.A, Basquin, C, Jayachandran, U, Conti, E.
登録日2011-09-09
公開日2011-11-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.743 Å)
主引用文献Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex.
Structure, 19, 2011
8EVG
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162bp CX3CR1 nucleosome (further classified with better nucleosome end)
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Tengfei, L, Ruifang, G, Yawen, B.
登録日2022-10-20
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Structural basis of cooperative targeting of the CX3CR1 nucleosome
To Be Published
6K1I
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Human nucleosome core particle with gammaH2A.X variant
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2AX, ...
著者Sharma, D, De Falco, L, Davey, C.A.
登録日2019-05-10
公開日2020-01-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
7K5Y
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Cryo-EM structure of a chromatosome containing human linker histone H1.4
分子名称: DNA (197-MER), Histone H1.4, Histone H2A type 1-B/E, ...
著者Zhou, B.-R, Bai, Y.
登録日2020-09-17
公開日2020-11-25
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
3U5P
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BU of 3u5p by Molmil
Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-28)K9me3K14acK18acK23ac histone peptide
分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2011-10-11
公開日2012-01-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
8SPU
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BU of 8spu by Molmil
Structure of ESRRB nucleosome bound OCT4 at site c
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8GUJ
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Bre1-nucleosome complex (Model II)
分子名称: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
登録日2022-09-12
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
8OO7
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CryoEM Structure INO80core Hexasome complex composite model state1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-04
公開日2023-07-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023

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