6V3N

Crystal structure of CDYL2 in complex with H3K27me3

Summary for 6V3N

Entry DOI	10.2210/pdb6v3n/pdb
Descriptor	Chromodomain Y-like protein 2, ACE-GLN-LEU-ALA-THR-LYS-ALA-ALA-ARG-M3L-SER-ALA-PRO-ALA-THR-TYR-NH2, UNKNOWN ATOM OR ION (3 entities in total)
Functional Keywords	chromodomain, epigenetics, structural genomics, structural genomics consortium, sgc, protein binding, gene regulation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	18683.08
Authors	Qin, S.,Tempel, W.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium,Structural Genomics Consortium (SGC) (deposition date: 2019-11-26, release date: 2020-04-01, Last modification date: 2023-10-11)
Primary citation	Dong, C.,Liu, Y.,Lyu, T.J.,Beldar, S.,Lamb, K.N.,Tempel, W.,Li, Y.,Li, Z.,James, L.I.,Qin, S.,Wang, Y.,Min, J. Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27:827-838.e7, 2020 Cited by PubMed: 32470319 DOI: 10.1016/j.chembiol.2020.05.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation