PDB: 320 resultsInfo pagesStatus searchChemie searchBIRD

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4M9V	Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... Authors: Liu, Y, Olanrewaju, Y.O, Zhang, X, Cheng, X. Deposit date: 2013-08-15 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.969 Å) Cite: DNA recognition of 5-carboxylcytosine by a zfp57 mutant at an atomic resolution of 0.97 angstrom. Biochemistry, 52, 2013
7EYI	Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation Descriptor: BORIC ACID, DNA (5'-D(*AP*TP*AP*GP*GP*GP*CP*CP*CP*CP*TP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*GP*GP*AP*AP*GP*GP*GP*GP*CP*CP*CP*TP*A)-3'), ... Authors: Yang, Y, Shi, Y.Y. Deposit date: 2021-05-31 Release date: 2021-09-01 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.401 Å) Cite: Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
8H9H	Crystal structure of ZBTB7A in complex with GACCC-containing sequence Descriptor: DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ... Authors: Yang, Y. Deposit date: 2022-10-25 Release date: 2023-04-26 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4. Febs J., 290, 2023
5N14	NMR structure calculation of a composite Cys2His2 type zinc finger protein containing a non-peptide (or oligourea) helical domain Descriptor: Protein (chimeric oligourea-peptide zinc finger), ZINC ION Authors: Venkateshaiah M, V.K, Salgado, G. Deposit date: 2017-02-05 Release date: 2017-04-12 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: NMR structure calculation of a composite Cys2His2 type zinc finger protein containing a non-peptide (or oligourea) helical domain. To Be Published
4R2E	Wilms Tumor Protein (WT1) zinc fingers in complex with methylated DNA Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), Wilms tumor protein, ... Authors: Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. Deposit date: 2014-08-11 Release date: 2014-10-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
2KMK	Gfi-1 Zinc Fingers 3-5 complexed with DNA Descriptor: DNA (5'-D(*CP*AP*TP*AP*AP*AP*TP*CP*AP*CP*TP*GP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*AP*GP*TP*GP*AP*TP*TP*TP*AP*TP*G)-3'), ZINC ION, ... Authors: Lee, S, Wu, Z. Deposit date: 2009-07-30 Release date: 2010-03-02 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of Gfi-1 zinc domain bound to consensus DNA. J.Mol.Biol., 397, 2010
8A4I	Crystal structure of SALL4 zinc finger cluster 4 with AT-rich DNA Descriptor: DNA (5'-D(*GP*AP*TP*AP*TP*TP*AP*AP*TP*AP*TP*C)-3'), MAGNESIUM ION, Sal-like protein 4, ... Authors: Watson, J.A, Pantier, R, Jayachandran, U, Chhatbar, K, Alexander-Howden, B, Kruusvee, V, Prendecki, M, Bird, A, Cook, A.G. Deposit date: 2022-06-11 Release date: 2023-01-11 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome. Life Sci Alliance, 6, 2023
4IS1	Crystal structure of ZNF217 bound to DNA Descriptor: 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ... Authors: Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. Deposit date: 2013-01-16 Release date: 2013-02-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. J.Biol.Chem., 288, 2013
2KVF	Structure of the three-Cys2His2 domain of mouse testis zinc finger protein Descriptor: ZINC ION, Zinc finger and BTB domain-containing protein 32 Authors: Chou, C.-C, Lou, Y.-C, Chen, C. Deposit date: 2010-03-15 Release date: 2010-04-14 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structure and DNA binding characteristics of the three-Cys(2)His(2) domain of mouse testis zinc finger protein. Proteins, 78, 2010
8JPY	Solution NMR Structure of Zinc-fingers 1 and 2 (fragment 257-320) from human Insulinoma-associated protein 1(INSM1) Descriptor: Insulinoma-associated protein 1, ZINC ION Authors: He, X.L, Yang, Y.H. Deposit date: 2023-06-13 Release date: 2024-06-19 Method: SOLUTION NMR Cite: Solution NMR Structure of Zinc-fingers 1 and 2 (fragment 257-320) from human Insulinoma-associated protein 1(INSM1) To Be Published
8JQ1	Solution NMR Structure of zinc fingers 1-2 (fragment 257-320) from human insulinoma-associated protein 1(INSM1) Descriptor: Insulinoma-associated protein 1, ZINC ION Authors: He, X.L, Yang, Y.H. Deposit date: 2023-06-13 Release date: 2024-06-19 Method: SOLUTION NMR Cite: Solution NMR Structure of zinc fingers 1-2 (fragment 257-320) from human insulinoma-associated protein 1(INSM1) To Be Published
7TXC	HIC2 zinc finger domain in complex with the DNA binding motif-2 of the BCL11A enhancer Descriptor: DNA (5'-D(*AP*CP*TP*GP*TP*TP*GP*GP*CP*AP*TP*TP*AP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*TP*AP*AP*TP*GP*CP*CP*AP*AP*CP*AP*GP*T)-3'), Hypermethylated in cancer 2 protein, ... Authors: Horton, J.R, Ren, R, Cheng, X. Deposit date: 2022-02-08 Release date: 2022-06-01 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.04 Å) Cite: HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nat.Genet., 54, 2022
4F2J	Crystal structure of ZNF217 bound to DNA, P6522 crystal form Descriptor: 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', ZINC ION, Zinc finger protein 217 Authors: Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. Deposit date: 2012-05-08 Release date: 2013-02-27 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.64 Å) Cite: New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217 J.Biol.Chem., 288, 2013
6E93	Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA Descriptor: DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... Authors: Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. Deposit date: 2018-07-31 Release date: 2018-11-07 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.747 Å) Cite: Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
3UK3	Crystal structure of ZNF217 bound to DNA Descriptor: 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ... Authors: Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. Deposit date: 2011-11-08 Release date: 2012-12-05 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Rediscovering DNA recognition by classical Zinc Fingers. To be Published
4GZN	Mouse ZFP57 zinc fingers in complex with methylated DNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... Authors: Liu, Y, Zhang, X, Cheng, X. Deposit date: 2012-09-06 Release date: 2012-10-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (0.99 Å) Cite: An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes Dev., 26, 2012
6E94	Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 K1055R in complex with methylated DNA Descriptor: DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... Authors: Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. Deposit date: 2018-07-31 Release date: 2018-11-07 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.594 Å) Cite: Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
5T0U	CTCF ZnF2-7 and DNA complex structure Descriptor: DNA (5'-D(*CP*CP*TP*CP*AP*CP*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*AP*GP*TP*GP*AP*GP*G)-3'), Transcriptional repressor CTCF, ... Authors: Hashimoto, H, Wang, D, Cheng, X. Deposit date: 2016-08-16 Release date: 2017-05-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.199 Å) Cite: Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
5T00	Human CTCF ZnF3-7 and methylated DNA complex Descriptor: DNA (5'-GCCAGCAGGGGG(5CM)GCTA-3'), DNA (5'-TAG(5CM)GCCCCCTGCTGGC-3'), Transcriptional repressor CTCF, ... Authors: Hashimoto, H, Wang, D, Cheng, X. Deposit date: 2016-08-15 Release date: 2017-05-24 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
3ZNF	HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF A SINGLE ZINC FINGER FROM A HUMAN ENHANCER BINDING PROTEIN IN SOLUTION Descriptor: ZINC FINGER, ZINC ION Authors: Gronenborn, A.M, Clore, G.M, Omichinski, J.G. Deposit date: 1990-07-09 Release date: 1992-01-15 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution. Biochemistry, 29, 1990
4M9E	Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA Descriptor: ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... Authors: Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X. Deposit date: 2013-08-14 Release date: 2014-02-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.851 Å) Cite: Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res., 42, 2014
6ML2	ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 1) Descriptor: DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ZINC ION, ... Authors: Horton, J.R, Cheng, X, Ren, R. Deposit date: 2018-09-26 Release date: 2019-07-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.874 Å) Cite: Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
6ML7	ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4 with a CpG 5mC Modification) Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*(5CM)P*GP*AP*AP*TP*T)-3'), ... Authors: Horton, J.R, Cheng, X, Ren, R. Deposit date: 2018-09-26 Release date: 2019-07-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
6ML3	ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 2) Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*CP*TP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ... Authors: Horton, J.R, Cheng, X, Ren, R. Deposit date: 2018-09-26 Release date: 2019-07-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.683 Å) Cite: Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
6VTX	Crystal structure of human KLF4 zinc finger DNA binding domain in complex with NANOG DNA Descriptor: DNA (5'-D(*AP*GP*GP*GP*GP*GP*TP*GP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*CP*AP*CP*CP*CP*CP*CP*T)-3'), Krueppel-like factor 4, ... Authors: Sharma, R, Sharma, S, Choi, K.J, Ferreon, A.C.M, Ferreon, J.C, Sankaran, B, MacKenzie, K.R, Kim, C. Deposit date: 2020-02-13 Release date: 2021-09-01 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization. Nat Commun, 12, 2021

 

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