5T00

Human CTCF ZnF3-7 and methylated DNA complex

Summary for 5T00

• Entry DOI: 10.2210/pdb5t00/pdb
• Related: 5T0U
• Descriptor: Transcriptional repressor CTCF, DNA (5'-TAG(5CM)GCCCCCTGCTGGC-3'), DNA (5'-GCCAGCAGGGGG(5CM)GCTA-3'), ... (5 entities in total)
• Functional Keywords: ccctc-binding factor, zinc finger, ctcf, transcription regulator-dna complex, transcription regulator/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 56630.23

Authors

Hashimoto, H.,Wang, D.,Cheng, X. (deposition date: 2016-08-15, release date: 2017-05-24, Last modification date: 2023-10-04)

• Primary citation: Hashimoto, H.,Wang, D.,Horton, J.R.,Zhang, X.,Corces, V.G.,Cheng, X.; Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.; Mol. Cell, 66:711-720.e3, 2017; PubMed: 28529057; DOI: 10.1016/j.molcel.2017.05.004

Experimental method

X-RAY DIFFRACTION (2.19 Å)