8RRP
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8RVT
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8Z4B
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8ONI
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![BU of 8oni by Molmil](/molmil-images/mine/8oni) | Human insulin in complex with the analytical antibody S1 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... | Authors: | Johansson, E. | Deposit date: | 2023-04-03 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
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8ONK
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8U4C
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![BU of 8u4c by Molmil](/molmil-images/mine/8u4c) | Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation. | Descriptor: | Insulin receptor, Insulin-like growth factor II | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2023-09-10 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8U4E
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![BU of 8u4e by Molmil](/molmil-images/mine/8u4e) | Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation. | Descriptor: | Insulin receptor, Insulin-like growth factor II | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2023-09-10 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8VJC
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![BU of 8vjc by Molmil](/molmil-images/mine/8vjc) | Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | Descriptor: | Insulin-like growth factor II, Isoform Short of Insulin receptor | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2024-01-06 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8VJB
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![BU of 8vjb by Molmil](/molmil-images/mine/8vjb) | Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation. | Descriptor: | Insulin-like growth factor II, Isoform Short of Insulin receptor | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2024-01-06 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8HGZ
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![BU of 8hgz by Molmil](/molmil-images/mine/8hgz) | Crystal structure of insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | DeMirci, H, Ayan, E. | Deposit date: | 2022-11-16 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
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8TAN
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![BU of 8tan by Molmil](/molmil-images/mine/8tan) | CryoEM structure of MFRV-VILP bound to IGF1Rzip | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor, ... | Authors: | Kirk, N.S. | Deposit date: | 2023-06-27 | Release date: | 2024-01-17 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression. Mol Metab, 80, 2024
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8HSF
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8HSK
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8CLS
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8IPZ
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8PI4
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8PJH
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8PI5
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8PI6
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![BU of 8pi6 by Molmil](/molmil-images/mine/8pi6) | Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension | Descriptor: | Insulin B chain,Insulin A chain | Authors: | Johansson, E, Schluckebier, G. | Deposit date: | 2023-06-21 | Release date: | 2023-11-08 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
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8PJC
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8SBD
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![BU of 8sbd by Molmil](/molmil-images/mine/8sbd) | Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C. | Deposit date: | 2023-04-03 | Release date: | 2023-08-30 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of insulin fibrillation. Sci Adv, 9, 2023
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7YRR
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![BU of 7yrr by Molmil](/molmil-images/mine/7yrr) | Cryo-EM structure of IGF1R with two IGF1 complex | Descriptor: | Insulin-like growth factor 1 receptor, Isoform 3 of Insulin-like growth factor I | Authors: | Xi, Z, Cang, W. | Deposit date: | 2022-08-10 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of IGF1R with two IGF1 complex at 4.3 angstroms resolution To Be Published
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7QAC
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![BU of 7qac by Molmil](/molmil-images/mine/7qac) | The T2 structure of polycrystalline cubic human insulin | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Karavassili, F, Triandafillidis, D.P, Valmas, A, Spiliopoulou, M, Fili, S, Kontou, P, Bowler, M.W, Von Dreele, R.B, Fitch, A, Margiolaki, I. | Deposit date: | 2021-11-16 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | POWDER DIFFRACTION (2.29 Å) | Cite: | The T 2 structure of polycrystalline cubic human insulin. Acta Crystallogr D Struct Biol, 79, 2023
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7Z5L
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7Z5Q
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![BU of 7z5q by Molmil](/molmil-images/mine/7z5q) | |