8CLS

Drosophila melanogaster insulin receptor ectodomain in complex with DILP5

Summary for 8CLS

• Entry DOI: 10.2210/pdb8cls/pdb
• EMDB information: 16718
• Descriptor: Insulin-like receptor, Probable insulin-like peptide 5 A chain, Probable insulin-like peptide 5 (3 entities in total)
• Functional Keywords: dilp5 hormone, drosophila insulin-like signalling receptor, disulfide linked ectodomain, signaling protein
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 8
• Total formula weight: 257590.38

Authors

Viola, C.M.,Brzozowski, A.M.,Shafi, T. (deposition date: 2023-02-17, release date: 2023-12-20)

• Primary citation: Viola, C.M.,Frittmann, O.,Jenkins, H.T.,Shafi, T.,De Meyts, P.,Brzozowski, A.M.; Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans.; Nat Commun, 14:6271-6271, 2023; PubMed: 37805602; DOI: 10.1038/s41467-023-41862-x

Experimental method

ELECTRON MICROSCOPY (4 Å)