8CLS

Drosophila melanogaster insulin receptor ectodomain in complex with DILP5

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
G	0005179	molecular_function	hormone activity
G	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCRNsCSfstLrayC

Chain	Residue	Details
C	CYS9-CYS23

---

site_id	PS01352
Number of Residues	77
Details	HEMATOPO_REC_L_F1 Long hematopoietin receptor, single chain family signature. VrVrWtppvdpngeivt....YEVayklqkpdqveekkcipaadfnqtagyLiklneglysfRvRansiag...YgdFtevehI

Chain	Residue	Details
A	VAL1224-ILE1300

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Repeat: {"description":"FU","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	204
Details	Domain: {"description":"Fibronectin type-III 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	190
Details	Domain: {"description":"Fibronectin type-III 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	20
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Peptide: {"description":"Insulin-like peptide 5 A chain","featureId":"PRO_0000016204","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---