8CLS

Drosophila melanogaster insulin receptor ectodomain in complex with DILP5

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
G	0005179	molecular_function	hormone activity
G	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCRNsCSfstLrayC

Chain	Residue	Details
C	CYS9-CYS23

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site_id	PS01352
Number of Residues	77
Details	HEMATOPO_REC_L_F1 Long hematopoietin receptor, single chain family signature. VrVrWtppvdpngeivt....YEVayklqkpdqveekkcipaadfnqtagyLiklneglysfRvRansiag...YgdFtevehI

Chain	Residue	Details
A	VAL1224-ILE1300

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	ASN356
A	ASN946
A	ASN1053
A	ASN1265
B	ASN356
B	ASN376
B	ASN406
B	ASN468
B	ASN509
B	ASN561
B	ASN569
A	ASN376
B	ASN751
B	ASN810
B	ASN946
B	ASN1053
B	ASN1265
A	ASN406
A	ASN468
A	ASN509
A	ASN561
A	ASN569
A	ASN751
A	ASN810

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site_id	SWS_FT_FI2
Number of Residues	12
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASN824
B	ASN898
B	ASN1147
B	ASN1218
A	ASN839
A	ASN864
A	ASN898
A	ASN1147
A	ASN1218
B	ASN824
B	ASN839
B	ASN864

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