8TAN

CryoEM structure of MFRV-VILP bound to IGF1Rzip

Summary for 8TAN

• Entry DOI: 10.2210/pdb8tan/pdb
• EMDB information: 41138
• Descriptor: Insulin-like growth factor 1 receptor, Insulin-like growth factor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: igf1r, mfrv-vilp, vilp, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 228542.13

Authors

Kirk, N.S. (deposition date: 2023-06-27, release date: 2024-01-17, Last modification date: 2024-01-31)

• Primary citation: Chrudinova, M.,Kirk, N.S.,Chuard, A.,Venugopal, H.,Zhang, F.,Lubos, M.,Gelfanov, V.,Panikova, T.,Zakova, L.,Cutone, J.,Mojares, M.,DiMarchi, R.,Jiracek, J.,Altindis, E.; A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.; Mol Metab, 80:101863-101863, 2024; PubMed: 38182007; DOI: 10.1016/j.molmet.2023.101863

Experimental method

ELECTRON MICROSCOPY (3.05 Å)