8TO0
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![BU of 8to0 by Molmil](/molmil-images/mine/8to0) | 48-nm repeating structure of doublets from mouse sperm flagella | Descriptor: | Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | Authors: | Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. | Deposit date: | 2023-08-02 | Release date: | 2023-11-01 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell, 186, 2023
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7NCC
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![BU of 7ncc by Molmil](/molmil-images/mine/7ncc) | Crystal structure of fructose-bisphosphate aldolase FBAP from Bacillus methanolicus | Descriptor: | D-MALATE, IMIDAZOLE, PHOSPHATE ION, ... | Authors: | Einsle, O, Zhang, L, Guetle, D, Jacquot, J.P. | Deposit date: | 2021-01-28 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Interrogating the Role of the Two Distinct Fructose-Bisphosphate Aldolases of Bacillus methanolicus by Site-Directed Mutagenesis of Key Amino Acids and Gene Repression by CRISPR Interference Front Microbiol, 12, 2021
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7NC7
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![BU of 7nc7 by Molmil](/molmil-images/mine/7nc7) | Crystal structure of fructose-bisphosphate aldolases FBAC from Bacillus methanolicus | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase | Authors: | Einsle, O, Zhang, L, Guetle, D, Jacquot, J.P. | Deposit date: | 2021-01-28 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Interrogating the Role of the Two Distinct Fructose-Bisphosphate Aldolases of Bacillus methanolicus by Site-Directed Mutagenesis of Key Amino Acids and Gene Repression by CRISPR Interference Front Microbiol, 12, 2021
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6S7X
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![BU of 6s7x by Molmil](/molmil-images/mine/6s7x) | dARC1 capsid domain dimer, orthorhombic form at 1.7 Angstrom | Descriptor: | Activity-regulated cytoskeleton associated protein 1, CHLORIDE ION, SODIUM ION | Authors: | Cottee, M.A, Taylor, I.A. | Deposit date: | 2019-07-07 | Release date: | 2020-01-15 | Last modified: | 2020-01-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure ofDrosophila melanogasterARC1 reveals a repurposed molecule with characteristics of retroviral Gag. Sci Adv, 6, 2020
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7A3W
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![BU of 7a3w by Molmil](/molmil-images/mine/7a3w) | Structure of Imine Reductase from Pseudomonas sp. | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, NAD(P)-dependent oxidoreductase, ... | Authors: | Cuetos, A, Thorpe, T, Turner, N.J, Grogan, G. | Deposit date: | 2020-08-18 | Release date: | 2021-08-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Multifunctional biocatalyst for conjugate reduction and reductive amination. Nature, 604, 2022
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8T6S
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![BU of 8t6s by Molmil](/molmil-images/mine/8t6s) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 10 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-18 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6T
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![BU of 8t6t by Molmil](/molmil-images/mine/8t6t) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 13 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-18 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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7AD2
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![BU of 7ad2 by Molmil](/molmil-images/mine/7ad2) | |
8T6O
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![BU of 8t6o by Molmil](/molmil-images/mine/8t6o) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 0 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-16 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6Y
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![BU of 8t6y by Molmil](/molmil-images/mine/8t6y) | SpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T78
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![BU of 8t78 by Molmil](/molmil-images/mine/8t78) | SpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T76
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![BU of 8t76 by Molmil](/molmil-images/mine/8t76) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 3 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T77
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![BU of 8t77 by Molmil](/molmil-images/mine/8t77) | SpRY-Cas9:gRNA complex bound to non-target DNA with 6 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8TZZ
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![BU of 8tzz by Molmil](/molmil-images/mine/8tzz) | SpG Cas9 with NGC PAM DNA target | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | Authors: | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | Deposit date: | 2023-08-28 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6P
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![BU of 8t6p by Molmil](/molmil-images/mine/8t6p) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 2 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-16 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T7S
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![BU of 8t7s by Molmil](/molmil-images/mine/8t7s) | SpRYmer bound to NAC PAM DNA | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-21 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6X
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![BU of 8t6x by Molmil](/molmil-images/mine/8t6x) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T79
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![BU of 8t79 by Molmil](/molmil-images/mine/8t79) | SpRY-Cas9:gRNA complex bound to non-target DNA with 10 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-20 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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7B5O
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![BU of 7b5o by Molmil](/molmil-images/mine/7b5o) | Cryo-EM structure of the human CAK bound to ICEC0942 at 2.5 Angstroms resolution | Descriptor: | (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ... | Authors: | Greber, B.J, Remis, J, Ali, S, Nogales, E. | Deposit date: | 2020-12-05 | Release date: | 2021-02-10 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | 2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942. Biophys.J., 120, 2021
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7B5Q
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![BU of 7b5q by Molmil](/molmil-images/mine/7b5q) | Cryo-EM structure of the human CAK bound to ICEC0942 (PHENIX-OPLS3e) | Descriptor: | (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ... | Authors: | Greber, B.J, Remis, J, Ali, S, Nogales, E. | Deposit date: | 2020-12-05 | Release date: | 2021-02-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | 2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942. Biophys.J., 120, 2021
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4W4H
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![BU of 4w4h by Molmil](/molmil-images/mine/4w4h) | Escherichia coli tryptophanase in holo form | Descriptor: | Tryptophanase | Authors: | Goldgur, Y. | Deposit date: | 2014-08-14 | Release date: | 2014-12-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structures of Escherichia coli tryptophanase in holo and `semi-holo' forms. Acta Crystallogr.,Sect.F, 71, 2015
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7QH6
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![BU of 7qh6 by Molmil](/molmil-images/mine/7qh6) | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1 | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L13, mitochondrial, ... | Authors: | Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. | Deposit date: | 2021-12-10 | Release date: | 2022-03-02 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13, 2022
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7ANT
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![BU of 7ant by Molmil](/molmil-images/mine/7ant) | Structure of CYP153A from Polaromonas sp. | Descriptor: | 1,2-ETHANEDIOL, Cytochrome P450, HEME C | Authors: | Zukic, E, Rowlinson, B, Sharma, M, Hoffman, S, Hauer, B, Grogan, G. | Deposit date: | 2020-10-12 | Release date: | 2021-04-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid Acs Catalysis, 11, 2021
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7AO7
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![BU of 7ao7 by Molmil](/molmil-images/mine/7ao7) | Structure of CYP153A from Polaromonas sp. in complex with octan-1-ol | Descriptor: | Cytochrome P450, OCTAN-1-OL, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zukic, E, Rowlinson, B, Sharma, M, Hoffmann, S, Hauer, B, Grogan, G. | Deposit date: | 2020-10-13 | Release date: | 2021-04-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid Acs Catalysis, 11, 2021
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7QH7
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![BU of 7qh7 by Molmil](/molmil-images/mine/7qh7) | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4 | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. | Deposit date: | 2021-12-10 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13, 2022
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