PDB: 92212 resultsInfo pagesStatus searchChemie searchBIRD

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8E97	PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2022-08-26 Release date: 2022-12-07 Last modified: 2022-12-14 Method: ELECTRON MICROSCOPY (4.19 Å) Cite: Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
8E92	D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2022-08-26 Release date: 2022-12-07 Last modified: 2022-12-14 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
8E99	Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2022-08-26 Release date: 2022-12-07 Last modified: 2022-12-14 Method: ELECTRON MICROSCOPY (4.24 Å) Cite: Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
8E98	D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in nanodisc - intact conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2022-08-26 Release date: 2022-12-07 Last modified: 2022-12-14 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
8E96	Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, GLYCINE, ... Authors: Kang, H, Furukawa, H. Deposit date: 2022-08-26 Release date: 2022-12-07 Last modified: 2022-12-14 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
6X3S	Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with bicuculline methbromide Descriptor: (5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. Deposit date: 2020-05-21 Release date: 2020-09-09 Last modified: 2020-09-23 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
5OTA	Structure of the periplasmic binding protein (PBP) NocT from Agrobacterium tumefaciens C58 in complex with octopinic acid Descriptor: (2~{S})-5-azanyl-2-[[(2~{R})-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]pentanoic acid, 1,2-ETHANEDIOL, Nopaline-binding periplasmic protein Authors: Vigouroux, A, Morera, S. Deposit date: 2017-08-21 Release date: 2017-12-20 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for high specificity of octopine binding in the plant pathogen Agrobacterium tumefaciens. Sci Rep, 7, 2017
3P10	Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol Descriptor: (2-thiophen-2-ylphenyl)methanol, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-09-29 Release date: 2010-11-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
3FFP	X ray structure of the complex between carbonic anhydrase II and LC inhibitors Descriptor: 2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide, BENZOIC ACID, Carbonic anhydrase 2, ... Authors: Temperini, C, Crocetti, L, Scozzafava, A, Supuran, C.T. Deposit date: 2008-12-04 Release date: 2009-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.81 Å) Cite: A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases Bioorg.Med.Chem.Lett., 19, 2009
6X40	Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus picrotoxin Descriptor: (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. Deposit date: 2020-05-21 Release date: 2020-09-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
3FJ4	Crystal structure of muconate lactonizing enzyme from Pseudomonas Fluorescens complexed with muconolactone Descriptor: MAGNESIUM ION, Muconate cycloisomerase, [(2S)-5-oxo-2,5-dihydrofuran-2-yl]acetic acid Authors: Fedorov, A.A, Fedorov, E.V, Sakai, A, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2008-12-14 Release date: 2009-03-31 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry, 48, 2009
6X3X	Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus diazepam Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, ... Authors: Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. Deposit date: 2020-05-21 Release date: 2020-09-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.92 Å) Cite: Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
3FUF	Leukotriene A4 hydrolase in complex with fragment 5-fluoroindole and bestatin Descriptor: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 5-fluoro-1H-indole, IMIDAZOLE, ... Authors: Davies, D.R. Deposit date: 2009-01-14 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3OIK	Human Carbonic anhydrase II mutant A65S, N67Q (CA IX mimic) bound by 2-Ethylestradiol 3,17-O,O-bis-sulfamate Descriptor: (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, Carbonic anhydrase 2, GLYCEROL, ... Authors: Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. Deposit date: 2010-08-19 Release date: 2011-07-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
3FU3	Leukotriene A4 hydrolase in complex with fragment 4-(2-amino-1,3-thiazol-4-yl)phenol Descriptor: 4-(2-amino-1,3-thiazol-4-yl)phenol, ACETATE ION, IMIDAZOLE, ... Authors: Davies, D.R. Deposit date: 2009-01-13 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FUK	Leukotriene A4 hydrolase in complex with 1-[2-(1H-indol-5-yloxy)ethyl]piperidine-4-carboxylic acid Descriptor: 1-[2-(1H-indol-5-yloxy)ethyl]piperidine-4-carboxylic acid, ACETATE ION, IMIDAZOLE, ... Authors: Davies, D.R. Deposit date: 2009-01-14 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FU0	Leukotriene A4 hydrolase in complex with fragment 4-(4-fluorobenzoyl)pyridine Descriptor: (4-fluorophenyl)(pyridin-4-yl)methanone, ACETATE ION, IMIDAZOLE, ... Authors: Davies, D.R. Deposit date: 2009-01-13 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FUH	Leukotriene A4 hydrolase in complex with fragment 5-hydroxyindole and bestatin Descriptor: 1H-indol-5-ol, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, IMIDAZOLE, ... Authors: Davies, D.R. Deposit date: 2009-01-14 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FTX	Leukotriene A4 hydrolase in complex with dihydroresveratrol and bestatin Descriptor: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol, ACETATE ION, ... Authors: Davies, D.R. Deposit date: 2009-01-13 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3U3U	Crystal structure of the tablysin-15-leukotriene E4 complex Descriptor: (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, CITRIC ACID, PRASEODYMIUM ION, ... Authors: Andersen, J.F. Deposit date: 2011-10-06 Release date: 2012-02-15 Last modified: 2015-01-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain. J.Biol.Chem., 287, 2012
3FUJ	Leukotriene A4 hydrolase in complex with 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole Descriptor: 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole, ACETATE ION, IMIDAZOLE, ... Authors: Davies, D.R. Deposit date: 2009-01-14 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FUA	L-FUCULOSE-1-PHOSPHATE ALDOLASE CRYSTAL FORM K Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, L-FUCULOSE-1-PHOSPHATE ALDOLASE, ... Authors: Dreyer, M.K, Schulz, G.E. Deposit date: 1996-02-14 Release date: 1996-10-14 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Catalytic mechanism of the metal-dependent fuculose aldolase from Escherichia coli as derived from the structure. J.Mol.Biol., 259, 1996
3FTV	Leukotriene A4 hydrolase in complex with fragment N-(pyridin-3-ylmethyl)aniline Descriptor: IMIDAZOLE, Leukotriene A-4 hydrolase, N-(pyridin-3-ylmethyl)aniline, ... Authors: Davies, D.R. Deposit date: 2009-01-13 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
7NDP	X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001856. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-bromanylspiro[3~{H}-chromene-2,4'-piperidine]-4-one, ... Authors: Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. Deposit date: 2021-02-02 Release date: 2021-04-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor. Rsc Adv, 11, 2021
4X9Q	MnSOD-3 Room Temperature Structure Descriptor: MALONATE ION, MANGANESE (II) ION, SULFATE ION, ... Authors: Hunter, G.J, Trinh, C.H, Hunter, T, Bonetta, R, Stewart, E.E. Deposit date: 2014-12-11 Release date: 2015-11-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.77 Å) Cite: The structure of the Caenorhabditis elegans manganese superoxide dismutase MnSOD-3-azide complex. Protein Sci., 24, 2015

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