3P10

Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol

Summary for 3P10

Entry DOI	10.2210/pdb3p10/pdb
Related	3P0Z 3f0d 3ieq 3ike 3ikf 3jvh 3k14 3ke1 3mbm
Descriptor	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CHLORIDE ION, ZINC ION, ... (7 entities in total)
Functional Keywords	seattle structural genomics center for infectious disease, ssgcid, ispf, cytidine, fol694, f69, mep pathway, isoprene biosynthesis, lyase, metal-binding
Biological source	Burkholderia pseudomallei
Total number of polymer chains	3
Total formula weight	59652.02
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2010-09-29, release date: 2010-11-10, Last modification date: 2024-02-21)
Primary citation	Begley, D.W.,Hartley, R.C.,Davies, D.R.,Edwards, T.E.,Leonard, J.T.,Abendroth, J.,Burris, C.A.,Bhandari, J.,Myler, P.J.,Staker, B.L.,Stewart, L.J. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12:63-76, 2011 Cited by PubMed: 21359640 DOI: 10.1007/s10969-011-9102-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation