3P10
Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | polymer | 183 | 19487.1 | 3 | UniProt (Q3JRA0) | Burkholderia pseudomallei | MECPS, MECDP-synthase |
| 2 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 3 | E, H, K (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F, I, L (A, B, C) | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE | non-polymer | 243.2 | 3 | Chemie (CTN) PubChem (16760387) PubChem (6175) PubChem (6253) PubChem (24729357) PubChem (25085165) PubChem (44264135) PubChem (44307610) PubChem (44356841) PubChem (45109772) PubChem (114682) PubChem (122948) PubChem (160696) PubChem (57764456) PubChem (57807005) PubChem (58460874) PubChem (58519508) PubChem (71230474) PubChem (59476533) PubChem (59713247) PubChem (60138999) PubChem (3013211) PubChem (66800112) PubChem (68199635) PubChem (453552) PubChem (54353063) PubChem (638040) PubChem (58899188) PubChem (1265901) PubChem (89495334) PubChem (596) PubChem (90089493) PubChem (70994952) PubChem (6480064) PubChem (5702244) PubChem (6476646) PubChem (6479885) PubChem (6551012) PubChem (6603781) PubChem (6713582) PubChem (117732781) PubChem (122468509) PubChem (12358851) PubChem (142117909) PubChem (148710634) PubChem (168266058) PubChem (171699434) | |||
| 5 | G (A) | (2-thiophen-2-ylphenyl)methanol | non-polymer | 190.3 | 1 | Chemie (F69) PubChem (2795559) | |||
| 6 | J (C) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 7 | M, N, O (A, B, C) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 162 (UniProt: Q3JRA0)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | expression tag |
| Ala -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| Met -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Thr -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Gln -6 | - | expression tag |
| Thr -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58461.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1190.7 | |
| All* | Total formula weight | 59652.0 |
