3JVH
Crystal structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 8395
Summary for 3JVH
Entry DOI | 10.2210/pdb3jvh/pdb |
Related | 3F0E 3F0G 3IEQ 3IEW 3IKE 3IKF |
Descriptor | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 5-[(pyridin-3-ylmethyl)amino]-1H-pyrazole-4-carboxamide, ... (5 entities in total) |
Functional Keywords | niaid, ssgcid, seattle dtructural genomics center for infectious disease, fragment crystallography, fragments of life, zinc-binding fragment, isoprene biosynthesis, lyase, metal-binding, structural genomics, seattle structural genomics center for infectious disease |
Biological source | Burkholderia pseudomallei (Pseudomonas pseudomallei) |
Total number of polymer chains | 3 |
Total formula weight | 59401.33 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2009-09-16, release date: 2009-09-29, Last modification date: 2023-09-06) |
Primary citation | Begley, D.W.,Hartley, R.C.,Davies, D.R.,Edwards, T.E.,Leonard, J.T.,Abendroth, J.,Burris, C.A.,Bhandari, J.,Myler, P.J.,Staker, B.L.,Stewart, L.J. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12:63-76, 2011 Cited by PubMed: 21359640DOI: 10.1007/s10969-011-9102-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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