8E99

Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4

Summary for 8E99

Entry DOI	10.2210/pdb8e99/pdb
EMDB information	27953 27954 27955 27957 27958 27959 27960 27961
Descriptor	Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, Glutamate receptor ionotropic, NMDA 2C, ... (6 entities in total)
Functional Keywords	ligand-gated ion channel, ionotropic glutamate receptor, synaptic protein, voltage-gate ion channel, transport protein-immune system complex, transport protein/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	403582.21
Authors	Chou, T.-H.,Furukawa, H. (deposition date: 2022-08-26, release date: 2022-12-07, Last modification date: 2022-12-14)
Primary citation	Chou, T.H.,Kang, H.,Simorowski, N.,Traynelis, S.F.,Furukawa, H. Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82:4548-, 2022 Cited by PubMed: 36309015 DOI: 10.1016/j.molcel.2022.10.008 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.24 Å)

Structure validation