PDB: 2917 resultsInfo pagesStatus searchChemie searchBIRD

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8EUQ	Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... Authors: Kassardjian, A, Julien, J.-P. Deposit date: 2022-10-19 Release date: 2023-04-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses. Cell Rep, 42, 2023
8ESB	CryoEM structure of HLA-A2 bound to MAGEA8 (232-241) peptide Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A8 peptide chimera Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8ESA	CryoEM structure of HLA-A2 bound to MAGEA4 (230-239) peptide Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A4 peptide chimera Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8ES9	CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8ES8	CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8DV1	SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to linker variant of affinity matured ACE2 mimetic CVD432 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion,Immunoglobulin gamma-1 heavy chain, Spike glycoprotein Authors: QCRG Structural Biology Consortium, Remesh, S.G, Merz, G.E, Brilot, A.F, Chio, U, Verba, K.A. Deposit date: 2022-07-27 Release date: 2022-08-31 Last modified: 2023-03-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31, 2023
8DV2	SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to computationally engineered ACE2 mimetic CVD293 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion, Spike glycoprotein Authors: QCRG Structural Biology Consortium, Remesh, S.G, Merz, G.E, Brilot, A.F, Chio, U, Verba, K.A. Deposit date: 2022-07-27 Release date: 2022-08-31 Last modified: 2023-03-15 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31, 2023
8EMA	mouse full length B cell receptor Descriptor: Anti-human Langerin 2G3 lambda chain, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, ... Authors: Ying, D, Xiong, P, Michael, R. Deposit date: 2022-09-27 Release date: 2022-11-16 Last modified: 2022-12-07 Method: ELECTRON MICROSCOPY (8.2 Å) Cite: Structural principles of B cell antigen receptor assembly. Nature, 612, 2022
8EK5	Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 Descriptor: 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... Authors: Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. Deposit date: 2022-09-20 Release date: 2023-12-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
8EMG	Crystal structure of a HLA-B*35:01-NP7 epitope from 2002 H2N1 influenza strain Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.83001268 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMF	Crystal structure of a HLA-B*35:01-NP6 epitope from 1977 H1N1 influenza strain Descriptor: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP6 epitope Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.80482423 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EO8	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain Descriptor: 3180 alpha chain, 3180 beta chain, Beta-2-microglobulin, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-10-02 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.300001 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EN8	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP4 epitope from 1972 influenza strain Descriptor: 3180 TCR alpha chain, 3180 TCR beta chain, Beta-2-microglobulin, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-29 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.700012 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8ENH	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP7 epitope from 2002 H3N2 influenza strain Descriptor: 3180 TCR alpha chain, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-30 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.500032 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMK	Crystal structure of HLA-B*35:01-NP3 epitope from 1957 H2N2 influenza strain Descriptor: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP3 epitope, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.66523 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMJ	Crystal structure of HLA-B*35:01-NP9 epitope from 2006 H1N1 influenza strain Descriptor: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP9 epitope Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.75002885 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMI	Crystal structure of a HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.57301509 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8F5A	Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10 Descriptor: ACETATE ION, Beta-2-microglobulin, CHLORIDE ION, ... Authors: Chatzileontiadou, D.S.M, Lobos, C.A, Gras, S. Deposit date: 2022-11-12 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10 To Be Published
8F7M	Crystal Structure of HLA-B*57:01-TW10-T242N complex Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... Authors: Chatzileontiadou, D.S.M, Lobos, C.A, Gras, S. Deposit date: 2022-11-18 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Crystal Structure of HLA-B*57:01-TW10-T242N complex To Be Published
8FHL	Structure of pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ... Authors: Custodio, J.M.F, Baker, B.M. Deposit date: 2022-12-14 Release date: 2023-06-28 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.194 Å) Cite: Structure of Pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd To Be Published
8FHU	Structure of Pyruvate dehydrogenase phosphatase regulatory subunit epitope presented by H2-Dd Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ... Authors: Custodio, J.M.F, Baker, B.M. Deposit date: 2022-12-15 Release date: 2023-06-28 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Structure of Pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd To Be Published
7K81	KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, Beta-2-microglobulin, ... Authors: MacLachlan, B.J, Rossjohn, J, Vivian, J.P. Deposit date: 2020-09-24 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1. J Immunol., 206, 2021
4HIX	Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide Descriptor: Beta-amyloid protein 40, Humanized 3D6 Fab heavy chain, Humanized 3D6 Fab light chain Authors: Miles, L.A, Crespi, G.A.N, Parker, M.W. Deposit date: 2012-10-12 Release date: 2013-03-13 Last modified: 2014-03-19 Method: X-RAY DIFFRACTION (2.204 Å) Cite: Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation. Sci Rep, 3, 2013
7K80	KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, ... Authors: MacLachlan, B.J, Rossjohn, J, Vivian, J.P. Deposit date: 2020-09-24 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1. J Immunol., 206, 2021
4HKJ	Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb) Descriptor: Beta-2-microglobulin, CPXV203 protein, H-2 class I histocompatibility antigen, ... Authors: McCoy IV, W.H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2012-10-15 Release date: 2012-11-14 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Mechanism of ER Retrieval of MHC Class I by Cowpox. Plos Biol., 10, 2012

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