8DV1
SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to linker variant of affinity matured ACE2 mimetic CVD432
Summary for 8DV1
Entry DOI | 10.2210/pdb8dv1/pdb |
EMDB information | 27730 |
Descriptor | Spike glycoprotein, Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion,Immunoglobulin gamma-1 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | sars-cov-2, spike, receptor-binding domain, ace2 receptor traps, antiviral protein, viral protein-antiviral protein complex, viral protein/antiviral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 2 |
Total formula weight | 245833.41 |
Authors | QCRG Structural Biology Consortium,Remesh, S.G.,Merz, G.E.,Brilot, A.F.,Chio, U.,Verba, K.A. (deposition date: 2022-07-27, release date: 2022-08-31, Last modification date: 2023-03-15) |
Primary citation | Remesh, S.G.,Merz, G.E.,Brilot, A.F.,Chio, U.S.,Rizo, A.N.,Pospiech Jr., T.H.,Lui, I.,Laurie, M.T.,Glasgow, J.,Le, C.Q.,Zhang, Y.,Diwanji, D.,Hernandez, E.,Lopez, J.,Mehmood, H.,Pawar, K.I.,Pourmal, S.,Smith, A.M.,Zhou, F.,DeRisi, J.,Kortemme, T.,Rosenberg, O.S.,Glasgow, A.,Leung, K.K.,Wells, J.A.,Verba, K.A. Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31:253-, 2023 Cited by PubMed: 36805129DOI: 10.1016/j.str.2023.01.009 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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