7TJQ
| SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | Authors: | Hsieh, C.-L, McLellan, J.S, Rush, S.A. | Deposit date: | 2022-01-16 | Release date: | 2022-09-14 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus. Cell Rep, 40, 2022
|
|
8PDY
| E. coli RNA polymerase paused at ops site | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-13 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
|
|
8QOI
| Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | Descriptor: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | Authors: | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | Deposit date: | 2023-09-29 | Release date: | 2024-06-12 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (1.9 Å) | Cite: | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Nat.Struct.Mol.Biol., 31, 2024
|
|
7L5W
| p97-R155H mutant dodecamer I | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | Deposit date: | 2020-12-23 | Release date: | 2021-08-04 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
|
|
7MWD
| HUWE1 in map with focus on HECT | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | Authors: | Hunkeler, M, Fischer, E.S. | Deposit date: | 2021-05-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81, 2021
|
|
7M99
| ATPgS bound TnsC filament from ShCAST system | Descriptor: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | Authors: | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | Deposit date: | 2021-03-30 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for target site selection in RNA-guided DNA transposition systems. Science, 373, 2021
|
|
7MWF
| HUWE1 in map with focus on interface | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | Authors: | Hunkeler, M, Fischer, E.S. | Deposit date: | 2021-05-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81, 2021
|
|
7MOP
| Cryo-EM structure of human HUWE1 in complex with DDIT4 | Descriptor: | DNA damage-inducible transcript 4 protein, E3 ubiquitin-protein ligase HUWE1 | Authors: | Hunkeler, M, Fischer, E.S. | Deposit date: | 2021-05-03 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81, 2021
|
|
7MWE
| HUWE1 in map with focus on WWE | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | Authors: | Hunkeler, M, Fischer, E.S. | Deposit date: | 2021-05-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81, 2021
|
|
7KOG
| Lethocerus Myosin II complete coiled-coil domain resolved in its native environment | Descriptor: | Myosin heavy chain isoform Mhc_X1 | Authors: | Rahmani, H, Hu, Z, Daneshparvar, N, Taylor, D, Taylor, K.A. | Deposit date: | 2020-11-09 | Release date: | 2021-03-24 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | The myosin II coiled-coil domain atomic structure in its native environment. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8VRC
| Tetrahymena thermophila MLP1 RRM domain | Descriptor: | LA motif RNA-binding domain protein | Authors: | Donaldson, L.W. | Deposit date: | 2024-01-21 | Release date: | 2024-09-04 | Method: | SOLUTION NMR | Cite: | NMR structure of the second RNA binding domain from Tetrahymena thermophila Mlp1 To Be Published
|
|
8S9S
| Structure of the human ER membrane protein complex (EMC) in GDN | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Tomaleri, G.P, Nguyen, V.N, Voorhees, R.M. | Deposit date: | 2023-03-30 | Release date: | 2023-05-17 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER. J.Cell Biol., 222, 2023
|
|
8SL0
| |
8G2M
| The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer | Descriptor: | CITRIC ACID, Heavy chain of humanized IgG, Light chain of humanized IgG, ... | Authors: | Williams, J.C, Williams, J.C. | Deposit date: | 2023-02-05 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer. J Immunother Cancer, 11, 2023
|
|
8SDK
| The MicroED structure of proteinase K crystallized by suspended drop crystallization | Descriptor: | CALCIUM ION, Proteinase K, SULFATE ION | Authors: | Gillman, C, Nicolas, W.J, Martynowycz, M.W, Gonen, T. | Deposit date: | 2023-04-06 | Release date: | 2023-05-31 | Last modified: | 2023-07-12 | Method: | ELECTRON CRYSTALLOGRAPHY (2.1 Å) | Cite: | Design and implementation of suspended drop crystallization. Iucrj, 10, 2023
|
|
8SLY
| Rat TRPV2 bound with 2 CBD ligands in nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 2, ... | Authors: | Tan, X, Swartz, K.J. | Deposit date: | 2023-04-24 | Release date: | 2023-05-31 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB. Elife, 12, 2023
|
|
8SLX
| Rat TRPV2 bound with 1 CBD ligand in nanodiscs | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily V member 2, cannabidiol | Authors: | Tan, X, Swartz, K.J. | Deposit date: | 2023-04-24 | Release date: | 2023-05-31 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB. Elife, 12, 2023
|
|
8GTR
| CryoEM structure of human Pannexin isoform 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Pannexin-3 | Authors: | Hussain, N, Penmatsa, A. | Deposit date: | 2022-09-08 | Release date: | 2024-02-28 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms. Nat Commun, 15, 2024
|
|
8GTT
| |
8G9S
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | AcrIC8, Cas11, Cas5, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-22 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
8G9U
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | CRISPR-associated protein, Csd1 family, Csd2 family, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-22 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
8GM3
| Vibrio harveyi Holo HphA | Descriptor: | HEME B/C, Hemophilin | Authors: | Pan, C, Shah, M, Moraes, T.F. | Deposit date: | 2023-03-24 | Release date: | 2024-03-27 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.727 Å) | Cite: | Prevalence of Slam-dependent hemophilins in Gram-negative bacteria. J.Bacteriol., 206, 2024
|
|
8GLO
| Haemophilus parainfluenzae Holo HphA | Descriptor: | CHLORIDE ION, HEME B/C, Hemophilin | Authors: | Shin, H.E, Ng, D, Moraes, T.F. | Deposit date: | 2023-03-22 | Release date: | 2024-03-27 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.937 Å) | Cite: | Prevalence of Slam-dependent hemophilins in Gram-negative bacteria. J.Bacteriol., 206, 2024
|
|
8ST7
| Structure of E3 ligase VsHECT bound to ubiquitin | Descriptor: | E3 ubiquitin-protein ligase SopA-like catalytic domain-containing protein, Ubiquitin, prop-2-en-1-amine | Authors: | Franklin, T.G, Pruneda, J.N. | Deposit date: | 2023-05-09 | Release date: | 2023-07-12 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Bacterial ligases reveal fundamental principles of polyubiquitin specificity. Mol.Cell, 83, 2023
|
|
8ST8
| |