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2OUE
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BU of 2oue by Molmil
Crystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolution
Descriptor: COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ...
Authors:Wedekind, J.E.
Deposit date:2007-02-10
Release date:2007-03-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
6HHX
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BU of 6hhx by Molmil
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)cytidine
Descriptor: 5'-O-(N-(L-aspartyl)-sulfamoyl)cytidine, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2018-08-29
Release date:2019-12-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
6HHV
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BU of 6hhv by Molmil
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)N3-methyluridine
Descriptor: 5'-O-(N-(L-aspartyl)-sulfamoyl)N3-methyluridine, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2018-08-29
Release date:2019-12-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
8IU6
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BU of 8iu6 by Molmil
Crystal structure of peptidyl-tRNA hydrolase mutant from Enterococcus faecium
Descriptor: GLYCEROL, Peptidyl-tRNA hydrolase
Authors:Pandey, R, Tripathi, S, Lanka, A.K, Zohib, M, Pal, R.K, Arora, A.
Deposit date:2023-03-23
Release date:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase mutant from Enterococcus faecium
To Be Published
6IX6
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BU of 6ix6 by Molmil
Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution
Descriptor: N-PROPANOL, Peptidyl-tRNA hydrolase
Authors:Viswanathan, V, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P.
Deposit date:2018-12-09
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution
To Be Published
7V8K
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BU of 7v8k by Molmil
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with L-Proline
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ...
Authors:Manickam, Y, Malhotra, N, Sharma, A.
Deposit date:2021-08-23
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with L-Proline
To Be Published
7V8J
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BU of 7v8j by Molmil
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with the reaction intermediates proline-adenylate (Pro-AMP) and pyrophosphate
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(R)-hydroxy{[(2S)-pyrrolidin-2-ylcarbonyl]oxy}phosphoryl]adenosine, PROLINE, ...
Authors:Manickam, Y, Malhotra, N, Sharma, A.
Deposit date:2021-08-23
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.519 Å)
Cite:Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with the reaction intermediates proline-adenylate (Pro-AMP) and pyrophosphate
To Be Published
6JKX
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BU of 6jkx by Molmil
Crystal structure of peptidyl-tRNA hydrolase with multiple sodium and chloride ions at 1.08 A resolution.
Descriptor: CHLORIDE ION, METHANOL, Peptidyl-tRNA hydrolase, ...
Authors:Viswanathan, V, Sharma, P, Bhushan, A, Sharma, S, Singh, T.P.
Deposit date:2019-03-03
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase with multiple sodium and chloride ions at 1.08 A resolution.
To Be Published
6JJ1
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BU of 6jj1 by Molmil
Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase
Authors:Iqbal, N, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P.
Deposit date:2019-02-24
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues
To Be Published
6JJQ
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BU of 6jjq by Molmil
Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.99 A resolution.
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Peptidyl-tRNA hydrolase, ...
Authors:Viswanathan, V, Bairagya, H.R, Sharma, P, Sharma, S, Singh, T.P.
Deposit date:2019-02-26
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.99 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.99 A resolution.
To Be Published
6OTE
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BU of 6ote by Molmil
Crystal Structure of Seryl-tRNA synthetase (SerRS) from Cryptosporidium parvum complexed with L-Serylsulfamoyl Adenosine
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Seryl-tRNA synthetase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-05-03
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of Seryl-tRNA synthetase (SerRS) from Cryptosporidium parvum complexed with L-Serylsulfamoyl Adenosine
to be published
2O5R
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BU of 2o5r by Molmil
Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution
Descriptor: CHLORIDE ION, GLYCEROL, Glutamyl-tRNA synthetase 1
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-12-06
Release date:2006-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution
To be published
3UFG
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BU of 3ufg by Molmil
The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glycyl-tRNA synthetase alpha subunit, LEUCINE
Authors:Tan, K, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-11-01
Release date:2011-11-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.552 Å)
Cite:The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC in complex with ATP
To be Published
8W8J
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BU of 8w8j by Molmil
Crystal structure of bacterial prolyl-tRNA synthetase in complex with inhibitor PAA-19
Descriptor: (2~{S})-~{N}-[3-(4-azanyl-5-fluoranyl-quinazolin-7-yl)phenyl]sulfonylpyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, Proline--tRNA ligase
Authors:Luo, Z, Zhou, H.
Deposit date:2023-09-03
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.807 Å)
Cite:Structure-Guided Fluorine Scanning Accelerates the Discovery of Potent and Selective Inhibitors Against Bacterial Prolyl-tRNA Synthetase
To Be Published
8W8L
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BU of 8w8l by Molmil
Crystal structure of bacterial prolyl-tRNA synthetase in complex with inhibitor PAA-38
Descriptor: (2~{S})-~{N}-[5-(4-azanyl-8-fluoranyl-quinazolin-7-yl)-2-fluoranyl-phenyl]sulfonylpyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Luo, Z, Zhou, H.
Deposit date:2023-09-03
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.824 Å)
Cite:Structure-Guided Fluorine Scanning Accelerates the Discovery of Potent and Selective Inhibitors Against Bacterial Prolyl-tRNA Synthetase
To Be Published
8W9I
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BU of 8w9i by Molmil
Crystal structure of bacterial prolyl-tRNA synthetase in complex with inhibitor PAA-5
Descriptor: (2~{S})-~{N}-[3-(4-azanylquinazolin-7-yl)phenyl]sulfonylpyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Luo, Z, Zhou, H.
Deposit date:2023-09-05
Release date:2024-09-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-Guided Fluorine Scanning Accelerates the Discovery of Potent and Selective Inhibitors Against Bacterial Prolyl-tRNA Synthetase
To Be Published
484D
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BU of 484d by Molmil
SOLUTION STRUCTURE OF HIV-1 REV PEPTIDE-RNA APTAMER COMPLEX
Descriptor: BASIC REV PEPTIDE, RNA APTAMER
Authors:Ye, X, Gorin, A.A, Frederick, R, Hu, W, Majumdar, A, Xu, W, Mclendon, G, Ellington, A, Patel, D.J.
Deposit date:1999-08-02
Release date:1999-10-14
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:RNA architecture dictates the conformations of a bound peptide.
Chem.Biol., 6, 1999
259D
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BU of 259d by Molmil
RNA HYDRATION: A DETAILED LOOK
Descriptor: RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3')
Authors:Egli, M, Portmann, S, Usman, N.
Deposit date:1996-05-03
Release date:1996-08-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:RNA hydration: a detailed look.
Biochemistry, 35, 1996
3LSQ
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BU of 3lsq by Molmil
Trypanosoma brucei seryl-tRNA synthetase
Descriptor: MALONATE ION, SODIUM ION, Seryl-tRNA synthetase
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2010-02-12
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray crystal structure of Seryl-tRNA synthetase from the eukaryotic parasite Trypanosoma brucei.
to be published
3LSS
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BU of 3lss by Molmil
Trypanosoma brucei seryl-tRNA synthetase in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MALONATE ION, SODIUM ION, ...
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2010-02-12
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:X-ray crystal structure of Seryl-tRNA synthetase from the eukaryotic parasite Trypanosoma brucei.
to be published
3M4P
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BU of 3m4p by Molmil
Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate
Descriptor: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparaginyl-tRNA synthetase, putative, ...
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2010-03-11
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:X-ray crystal structure of asparaginyl-tRNA synthetase from the eukaryotic human pathogen Entamoeba histolytica.
to be published
3NET
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BU of 3net by Molmil
Crystal structure of histidyl-tRNA synthetase from Nostoc sp. PCC 7120
Descriptor: ACETATE ION, Histidyl-tRNA synthetase
Authors:Chang, C, Bigelow, L, Carroll, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-06-09
Release date:2010-08-04
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of histidyl-tRNA synthetase from Nostoc sp. PCC 7120
To be Published
7EIV
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BU of 7eiv by Molmil
heterotetrameric glycyl-tRNA synthetase from Escherichia coli
Descriptor: GLYCINE, Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, ...
Authors:Ju, Y, Zhou, H.
Deposit date:2021-03-31
Release date:2021-08-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications.
Nucleic Acids Res., 49, 2021
5MP0
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BU of 5mp0 by Molmil
Human m7GpppN-mRNA Hydrolase (DCP2, NUDT20) Catalytic Domain
Descriptor: 1,2-ETHANEDIOL, m7GpppN-mRNA hydrolase
Authors:Mathea, S, Salah, E, Velupillai, S, Tallant, C, Pike, A.C.W, Bushell, S.R, Faust, B, Wang, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Huber, K.
Deposit date:2016-12-15
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Human m7GpppN-mRNA Hydrolase (DCP2, NUDT20) Catalytic Domain
To Be Published
4LZZ
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BU of 4lzz by Molmil
Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transcriptional regulator (NtrC family), ...
Authors:Sysoeva, T.A, Chowdhury, S, Guo, L, Nixon, B.T.
Deposit date:2013-08-01
Release date:2013-12-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Nucleotide-induced asymmetry within ATPase activator ring drives sigma 54-RNAP interaction and ATP hydrolysis.
Genes Dev., 27, 2013

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