219D

DNA/RNA HYBRID DUPLEX (5'-D(*GP*CP*TP*AP*TP*AP*APS*TP*GP*G)-3')(DOT) (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3') WITH A PHOSPHOROTHIOATE MOIETY

Summary for 219D

• Entry DOI: 10.2210/pdb219d/pdb
• Descriptor: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*TP*GP*G)-3'), RNA (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3') (2 entities in total)
• Functional Keywords: dna, rna, hybrid, phosphorothioate, dna-rna complex, dna-rna hybrid
• Total number of polymer chains: 2
• Total formula weight: 6222.01

Authors

Gonzalez, C.,James, T.L. (deposition date: 1995-07-25, release date: 1995-10-15, Last modification date: 2022-03-09)

• Primary citation: Gonzalez, C.,Stec, W.,Reynolds, M.A.,James, T.L.; Structure and dynamics of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety: NMR and molecular dynamics with conventional and time-averaged restraints.; Biochemistry, 34:4969-4982, 1995; PubMed: 7711019; DOI: 10.1021/bi00015a008

Experimental method

SOLUTION NMR