8BC6
 
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1U2E
 | | Crystal Structure of the C-C bond hydrolase MhpC | | Descriptor: | 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase, CHLORIDE ION | | Authors: | Montgomery, M.G, Dunn, G, Mohammed, F, Robertson, T, Garcia, J.-L, Coker, A, Bugg, T.D.H, Wood, S.P. | | Deposit date: | 2004-07-19 | | Release date: | 2005-02-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Structure of the C-C Bond Hydrolase MhpC Provides Insights into its Catalytic Mechanism
J.Mol.Biol., 346, 2005
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8BEL
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CIII membrane domain) | | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | | Authors: | Klusch, N, Kuehlbrandt, W. | | Deposit date: | 2022-10-21 | | Release date: | 2023-01-11 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.25 Å) | | Cite: | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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8AW4
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1U34
 | | 3D NMR structure of the first extracellular domain of CRFR-2beta, a type B1 G-protein coupled receptor | | Descriptor: | Corticotropin releasing factor receptor 2 | | Authors: | Grace, C.R, Perrin, M.H, DiGruccio, M.R, Miller, C.L, Rivier, J.E, Vale, W.W, Riek, R. | | Deposit date: | 2004-07-20 | | Release date: | 2004-09-07 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor
Proc.Natl.Acad.Sci.USA, 101, 2004
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1UGO
 | | Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5 | | Descriptor: | Bcl2-associated athanogene 5 | | Authors: | Endoh, H, Hayashi, F, Seimiya, K, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-17 | | Release date: | 2004-08-03 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
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8B8W
 | | Crystal structure of PPARG and NCOR2 with an inverse agonist (compound 7a) | | Descriptor: | 4-chloranyl-~{N}3-phenyl-~{N}1-(phenylmethyl)benzene-1,3-dicarboxamide, GLYCEROL, Nuclear receptor corepressor 2, ... | | Authors: | Friberg, A, Orsi, D.L, Pook, E, Siegel, S, Lemke, C.T, Stellfeld, T, Puetter, V, Goldstein, J. | | Deposit date: | 2022-10-05 | | Release date: | 2022-12-28 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists.
Bioorg.Med.Chem., 78, 2022
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1UCV
 | | Sterile alpha motif (SAM) domain of ephrin type-A receptor 8 | | Descriptor: | EPHRIN TYPE-A RECEPTOR 8 | | Authors: | Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-04-23 | | Release date: | 2004-05-11 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of Sterile alpha motif (SAM) domain of ephrin type-A receptor 8
To be Published
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8B91
 | | Crystal structure of mutant PPARG (C313A) and NCOR2 with an inverse agonist (compound SI-1) | | Descriptor: | Nuclear receptor corepressor 2, Peroxisome proliferator-activated receptor gamma, ~{N}3-[4-[bis(fluoranyl)methoxy]-3-fluoranyl-phenyl]-4-chloranyl-6-fluoranyl-~{N}1-[(2-methoxyphenyl)methyl]benzene-1,3-dicarboxamide | | Authors: | Friberg, A, Orsi, D.L, Pook, E, Siegel, S, Lemke, C.T, Stellfeld, T, Puetter, V, Goldstein, J. | | Deposit date: | 2022-10-05 | | Release date: | 2022-12-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists.
Bioorg.Med.Chem., 78, 2022
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8AVX
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1UDL
 | | The solution structure of the fifth SH3 domain of intersectin 2 (KIAA1256) | | Descriptor: | intersectin 2 | | Authors: | Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-05-01 | | Release date: | 2003-11-01 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the fifth SH3 domain of intersectin 2 (KIAA1256)
To be Published
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8BI9
 | | Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase (T112W/T116E variant) | | Descriptor: | Nitric oxide synthase, brain, TERTIARY-BUTYL ALCOHOL | | Authors: | Balboa, J.R, Ostergaard, S, Stromgaard, K, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | | Deposit date: | 2022-11-01 | | Release date: | 2022-12-21 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction.
J.Med.Chem., 66, 2023
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1UEX
 | | Crystal structure of von Willebrand Factor A1 domain complexed with snake venom bitiscetin | | Descriptor: | bitiscetin alpha chain, bitiscetin beta chain, von Willebrand Factor | | Authors: | Maita, N, Nishio, K, Nishimoto, E, Matsui, T, Shikamoto, Y, Morita, T, Sadler, J.E, Mizuno, H. | | Deposit date: | 2003-05-22 | | Release date: | 2003-09-30 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Crystal structure of von Willebrand factor A1 domain complexed with snake venom, bitiscetin. Insight into glycoprotein Ibalpha binding mechanism induced by snake venom proteins.
J.Biol.Chem., 278, 2003
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8BEK
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1U47
 | | cytosine-8-Oxoguanine base pair at the polymerase active site | | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | | Deposit date: | 2004-07-23 | | Release date: | 2004-09-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
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8BF5
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1U4O
 | | Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2,6-DICARBOXYNAPHTHALENE, L-lactate dehydrogenase | | Authors: | Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. | | Deposit date: | 2004-07-26 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
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1UF3
 | | Crystal structure of TT1561 of thermus thermophilus HB8 | | Descriptor: | CALCIUM ION, hypothetical protein TT1561 | | Authors: | Kato-Murayama, M, Shirouzu, M, Terada, T, Murayama, K, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-05-23 | | Release date: | 2003-11-23 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of TT1561 of thermus thermophilus HB8
To be Published
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8B8Q
 | | Structure of mTMEM16F in lipid Nanodiscs in the presence of Ca2+ | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-12-21 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8AT8
 | | Structure of coproporphyrin III-LmCpfC | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Gabler, T, Hofbauer, S. | | Deposit date: | 2022-08-22 | | Release date: | 2022-12-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation.
Protein Sci., 32, 2023
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1UG1
 | | SH3 domain of Hypothetical protein BAA76854.1 | | Descriptor: | KIAA1010 protein | | Authors: | Nagata, T, Muto, Y, Kamewari, Y, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-11 | | Release date: | 2003-12-11 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | NMR structure of SH3 domain of Hypothetical protein BAA76854.1
To be Published
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1UGM
 | | Crystal Structure of LC3 | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3 | | Authors: | Sugawara, K, Suzuki, N.N, Fujioka, Y, Mizushima, N, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2003-06-16 | | Release date: | 2004-07-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8
Genes Cells, 9, 2004
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8B7W
 | | Complex IL-17A/anti-IL-17A-76 | | Descriptor: | CHLORIDE ION, GLYCEROL, Interleukin-17A, ... | | Authors: | Kostareva, O.S, Svoeglazova, A, Kolyadenko, I.A, Dzhus, U.F, Tishchenko, S.V, Gabdulkhakov, A.G. | | Deposit date: | 2022-10-03 | | Release date: | 2022-12-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Two Epitope Regions Revealed in the Complex of IL-17A and Anti-IL-17A V H H Domain.
Int J Mol Sci, 23, 2022
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1UGT
 | | Structural Studies of Cu(I)-Bleomycin | | Descriptor: | BLEOMYCIN A2, COBALT (II) ION | | Authors: | Lehmann, T.E. | | Deposit date: | 2003-06-18 | | Release date: | 2004-04-27 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structural study of copper(I)-bleomycin.
J.Biol.Inorg.Chem., 9, 2004
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8B5B
 | | Human BRD4 bromdomain 1 in complex with a H4 peptide containing acetyl lysine and ApmTri (H4K5acK8ApmTri) | | Descriptor: | Bromodomain-containing protein 4, DI(HYDROXYETHYL)ETHER, H4K5acK8ApmTri | | Authors: | Braun, M.B, Bartlick, N, Stehle, T. | | Deposit date: | 2022-09-22 | | Release date: | 2023-01-11 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family.
Angew.Chem.Int.Ed.Engl., 62, 2023
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