1U4O
Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid
Summary for 1U4O
| Entry DOI | 10.2210/pdb1u4o/pdb |
| Related | 1U5C 1u4s 1u5a |
| Descriptor | L-lactate dehydrogenase, 2,6-DICARBOXYNAPHTHALENE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
| Functional Keywords | protein-ligand complex, oxidoreductase |
| Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
| Total number of polymer chains | 1 |
| Total formula weight | 35298.93 |
| Authors | Conners, R.,Cameron, A.,Read, J.,Schambach, F.,Sessions, R.B.,Brady, R.L. (deposition date: 2004-07-26, release date: 2005-06-21, Last modification date: 2023-08-23) |
| Primary citation | Conners, R.,Schambach, F.,Read, J.,Cameron, A.,Sessions, R.B.,Vivas, L.,Easton, A.,Croft, S.L.,Brady, R.L. Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol.Biochem.Parasitol., 142:137-148, 2005 Cited by PubMed: 15978953DOI: 10.1016/j.molbiopara.2005.03.015 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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