PDB: 286 resultsInfo pagesStatus searchChemie searchBIRD

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2YVX	Crystal structure of magnesium transporter MgtE Descriptor: MAGNESIUM ION, Mg2+ transporter MgtE Authors: Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O. Deposit date: 2007-04-18 Release date: 2007-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Crystal structure of the MgtE Mg(2+) transporter Nature, 448, 2007
3TDH	Structure of the regulatory fragment of sccharomyces cerevisiae AMPK in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... Authors: Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D. Deposit date: 2011-08-11 Release date: 2011-11-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
4EAI	Co-crystal structure of an AMPK core with AMP Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... Authors: Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. Deposit date: 2012-03-22 Release date: 2012-06-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.285 Å) Cite: AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAK	Co-crystal structure of an AMPK core with ATP Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... Authors: Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. Deposit date: 2012-03-22 Release date: 2012-06-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAJ	Co-crystal of AMPK core with AMP soaked with ATP Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... Authors: Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. Deposit date: 2012-03-22 Release date: 2012-06-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.609 Å) Cite: AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAG	Co-crystal structure of an chimeric AMPK core with ATP Descriptor: 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. Deposit date: 2012-03-22 Release date: 2012-06-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.701 Å) Cite: AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAL	Co-crystal of AMPK core with ATP soaked with AMP Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... Authors: Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. Deposit date: 2012-03-22 Release date: 2012-06-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.506 Å) Cite: AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
2OUX	Crystal structure of the soluble part of a magnesium transporter Descriptor: MAGNESIUM ION, Magnesium transporter Authors: Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2007-02-12 Release date: 2007-03-20 Last modified: 2021-02-03 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Structural studies on cytosolic domain of magnesium transporter MgtE from Enterococcus faecalis. Proteins, 78, 2010
2OOX	Crystal structure of the adenylate sensor from AMP-activated protein kinase complexed with AMP Descriptor: ADENOSINE MONOPHOSPHATE, Hypothetical protein C1556.08c in chromosome I, SNF1-like protein kinase ssp2, ... Authors: Townley, R, Shapiro, L. Deposit date: 2007-01-26 Release date: 2007-02-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Science, 315, 2007
2OOY	Crystal structure of the adenylate sensor from AMP-activated protein kinase complexed with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CITRATE ANION, Hypothetical protein C1556.08c in chromosome I, ... Authors: Townley, R, Shapiro, L. Deposit date: 2007-01-26 Release date: 2007-02-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Science, 315, 2007
2QRD	Crystal Structure of the Adenylate Sensor from AMP-activated Protein Kinase in complex with ADP and ATP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Protein C1556.08c, ... Authors: Jin, X, Townley, R, Shapiro, L. Deposit date: 2007-07-28 Release date: 2007-10-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
2QH1	Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state Descriptor: FE (II) ION, Hypothetical protein Ta0289 Authors: Singer, A.U, Proudfoot, M, Brown, G, Xu, L, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) Deposit date: 2007-06-29 Release date: 2008-02-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain. J.Mol.Biol., 375, 2008
2QRE	Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranotide (ZMP) Descriptor: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Protein C1556.08c, SNF1-like protein kinase ssp2, ... Authors: Jin, X, Townley, R, Shapiro, L. Deposit date: 2007-07-28 Release date: 2007-10-23 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
2QLV	Crystal structure of the heterotrimer core of the S. cerevisiae AMPK homolog SNF1 Descriptor: Carbon catabolite derepressing protein kinase, Nuclear protein SNF4, Protein SIP2 Authors: Amodeo, G.A, Rudolph, M.J, Tong, L. Deposit date: 2007-07-13 Release date: 2007-09-25 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1. Nature, 449, 2007
2QR1	Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, Protein C1556.08c, SNF1-like protein kinase ssp2, ... Authors: Jin, X, Townley, R, Shapiro, L. Deposit date: 2007-07-27 Release date: 2007-10-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
6XWL	Cystathionine beta-synthase from Toxoplasma gondii Descriptor: Cystathionine beta-synthase, PYRIDOXAL-5'-PHOSPHATE Authors: Fernandez-Rodriguez, C, Oyenarte, I, Conter, C, Gonzalez-Recio, I, Quintana, I, Martinez-Chantar, M, Astegno, A, Martinez-Cruz, L.A. Deposit date: 2020-01-23 Release date: 2021-02-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.201 Å) Cite: Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii . Comput Struct Biotechnol J, 19, 2021
5EZV	X-ray crystal structure of AMP-activated protein kinase alpha-2/alpha-1 RIM chimaera (alpha-2(1-347)/alpha-1(349-401)/alpha-2(397-end) beta-1 gamma-1) co-crystallized with C2 (5-(5-hydroxyl-isoxazol-3-yl)-furan-2-phosphonic acid) Descriptor: 3-[4-(2-hydroxyphenyl)phenyl]-4-oxidanyl-6-oxidanylidene-7H-thieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-2/alpha-1 RIM SWAP chimera, 5'-AMP-activated protein kinase subunit beta-1, ... Authors: Langendorf, C.G, Kemp, B.E. Deposit date: 2015-11-26 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding. Nat Commun, 7, 2016
8CGY	Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... Authors: Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Duden, R, Bourenkov, G, Schneider, T, Redecke, L. Deposit date: 2023-02-06 Release date: 2024-02-21 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3 Å) Cite: A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15, 2024
1ME9	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP bound Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, POTASSIUM ION Authors: Prosise, G.L, Luecke, H. Deposit date: 2002-08-08 Release date: 2003-08-12 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1MEW	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and NAD bound Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ... Authors: Prosise, G.L, Luecke, H. Deposit date: 2002-08-08 Release date: 2003-08-12 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
7OJ1	Bacillus subtilis IMPDH in complex with Ap4A Descriptor: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION Authors: Giammarinaro, P.I, Bange, G. Deposit date: 2021-05-13 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
5TSR	Crystal structure of PRL-3 phosphatase in complex with the Bateman domain of CNNM3 magnesium transporter Descriptor: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 3 Authors: Kozlov, G, Zhang, H, Gehring, K. Deposit date: 2016-10-31 Release date: 2017-02-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.188 Å) Cite: PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3. Sci Rep, 7, 2017
5UFU	Structure of AMPK bound to activator Descriptor: 1,4:3,6-dianhydro-2-O-(6-chloro-5-{4-[1-(hydroxymethyl)cyclopropyl]phenyl}-1H-benzimidazol-2-yl)-D-mannitol, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ... Authors: Calabrese, M.F, Kurumbail, R.G. Deposit date: 2017-01-05 Release date: 2017-05-17 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice. Cell Metab., 25, 2017
7OY9	Crystal structure of GMP reductase from mycobacterium smegmatis. Descriptor: Guanosine 5'-monophosphate reductase Authors: Dolezal, M, Klima, M, Pichova, I. Deposit date: 2021-06-24 Release date: 2022-04-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-beta-synthase domain. Febs J., 289, 2022
1B3O	TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE Descriptor: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), ... Authors: Colby, T.D, Vanderveen, K, Strickler, M.D, Goldstein, B.M. Deposit date: 1998-12-14 Release date: 1999-04-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Proc.Natl.Acad.Sci.USA, 96, 1999

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