4EAJ
Co-crystal of AMPK core with AMP soaked with ATP
Summary for 4EAJ
Entry DOI | 10.2210/pdb4eaj/pdb |
Related | 4EAG 4EAI 4EAK 4EAL |
Descriptor | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... (6 entities in total) |
Functional Keywords | ampk, transferase |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm : P54645 |
Total number of polymer chains | 3 |
Total formula weight | 60780.21 |
Authors | Chen, L.,Wang, J.,Zhang, Y.-Y.,Yan, S.F.,Neumann, D.,Schlattner, U.,Wang, Z.-X.,Wu, J.-W. (deposition date: 2012-03-22, release date: 2012-06-06, Last modification date: 2023-11-08) |
Primary citation | Chen, L.,Wang, J.,Zhang, Y.-Y.,Yan, S.F.,Neumann, D.,Schlattner, U.,Wang, Z.-X.,Wu, J.-W. AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19:716-718, 2012 Cited by PubMed: 22659875DOI: 10.1038/nsmb.2319 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.609 Å) |
Structure validation
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