8CGY
Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing
Summary for 8CGY
Entry DOI | 10.2210/pdb8cgy/pdb |
Descriptor | Inosine-5'-monophosphate dehydrogenase, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | imp dehydrogenase, purine biosynthetic enzyme, native cofactors, transferase |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 113622.02 |
Authors | Boger, J.,Schoenherr, R.,Lahey-Rudolph, J.M.,Harms, M.,Kaiser, J.,Nachtschatt, S.,Wobbe, M.,Duden, R.,Bourenkov, G.,Schneider, T.,Redecke, L. (deposition date: 2023-02-06, release date: 2024-02-21, Last modification date: 2024-03-06) |
Primary citation | Schonherr, R.,Boger, J.,Lahey-Rudolph, J.M.,Harms, M.,Kaiser, J.,Nachtschatt, S.,Wobbe, M.,Duden, R.,Konig, P.,Bourenkov, G.,Schneider, T.R.,Redecke, L. A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15:1709-1709, 2024 Cited by PubMed: 38402242DOI: 10.1038/s41467-024-45985-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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