5OOW
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![BU of 5oow by Molmil](/molmil-images/mine/5oow) | Crystal structure of lobe II from the nucleotide binding domain of DnaK in complex with AMPPCP | Descriptor: | Chaperone protein DnaK, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Jakob, R.P, Bauer, D, Meinhold, S, Stigler, J, Merkel, U, Maier, T, Rief, M, Zoldak, G. | Deposit date: | 2017-08-09 | Release date: | 2018-04-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7F58
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![BU of 7f58 by Molmil](/molmil-images/mine/7f58) | Cryo-EM structure of THIQ-MC4R-Gs_Nb35 complex | Descriptor: | (3R)-N-[(2R)-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-(1,2,4-triazol-1-ylmethyl)piperidin-1-yl]-1-oxidanylidene-propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | Deposit date: | 2021-06-21 | Release date: | 2021-11-03 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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6E9D
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![BU of 6e9d by Molmil](/molmil-images/mine/6e9d) | Sub-2 Angstrom Ewald Curvature-Corrected Single-Particle Cryo-EM Reconstruction of AAV-2 L336C | Descriptor: | Capsid protein VP1 | Authors: | Tan, Y.Z, Aiyer, S, Mietzsch, M, Hull, J.A, McKenna, R, Baker, T.S, Agbandje-McKenna, M, Lyumkis, D. | Deposit date: | 2018-07-31 | Release date: | 2018-08-15 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (1.86 Å) | Cite: | Sub-2 angstrom Ewald curvature corrected structure of an AAV2 capsid variant. Nat Commun, 9, 2018
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7JI3
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7FIX
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![BU of 7fix by Molmil](/molmil-images/mine/7fix) | |
6U2O
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6S83
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![BU of 6s83 by Molmil](/molmil-images/mine/6s83) | Crystal structure of methionine adenosyltransferase from Pyrococcus furiosus in complex with AMPPCP, SAM, and PCP | Descriptor: | MAGNESIUM ION, METHYLENEDIPHOSPHONIC ACID, PHOSPHATE ION, ... | Authors: | Degano, M, Minici, C, Porcelli, M. | Deposit date: | 2019-07-08 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.336 Å) | Cite: | Structures of catalytic cycle intermediates of the Pyrococcus furiosus methionine adenosyltransferase demonstrate negative cooperativity in the archaeal orthologues. J.Struct.Biol., 210, 2020
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8B3S
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![BU of 8b3s by Molmil](/molmil-images/mine/8b3s) | Structure of YjbA in complex with ClpC N-terminal Domain | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpC / Negative regulator of tic competence clcC/mecB, GLYCEROL, MAGNESIUM ION, ... | Authors: | Evans, N.J, Isaacson, R.L, Camp, A.H, Collins, M.K. | Deposit date: | 2022-09-16 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structure of YjbA in complex with ClpC N-terminal Domain To Be Published
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7A4O
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![BU of 7a4o by Molmil](/molmil-images/mine/7a4o) | Structure of DYRK1A in complex with AMPNP | Descriptor: | Dual specificity tyrosine-phosphorylation-regulated kinase 1A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Dokurno, P, Surgenor, A.E, Hubbard, R.E. | Deposit date: | 2020-08-20 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B. J.Med.Chem., 64, 2021
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8T8E
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![BU of 8t8e by Molmil](/molmil-images/mine/8t8e) | cryoEM structure of Smc5/6 5mer | Descriptor: | DNA repair protein KRE29, Non-structural maintenance of chromosome element 5, Structural maintenance of chromosomes protein 6 | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-06-22 | Release date: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions. Proc.Natl.Acad.Sci.USA, 120, 2023
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8T8F
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![BU of 8t8f by Molmil](/molmil-images/mine/8t8f) | Smc5/6 8mer | Descriptor: | DNA repair protein KRE29, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosome element 5, ... | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-06-22 | Release date: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions. Proc.Natl.Acad.Sci.USA, 120, 2023
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4CQ4
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![BU of 4cq4 by Molmil](/molmil-images/mine/4cq4) | C-terminal fragment of Af1503-sol: transmembrane receptor Af1503 from Archaeoglobus fulgidus engineered for solubility | Descriptor: | ENGINEERED VERSION OF TRANSMEMBRANE RECEPTOR AF1503 | Authors: | Hartmann, M.D, Dunin-Horkawicz, S, Hulko, M, Martin, J, Coles, M, Lupas, A.N. | Deposit date: | 2014-02-11 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Soluble Mutant of the Transmembrane Receptor Af1503 Features Strong Changes in Coiled-Coil Periodicity. J.Struct.Biol., 186, 2014
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6UQS
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5LG7
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![BU of 5lg7 by Molmil](/molmil-images/mine/5lg7) | Solution NMR structure of Tryptophan to Arginine mutant of Arkadia RING domain | Descriptor: | E3 ubiquitin-protein ligase Arkadia, ZINC ION | Authors: | Birkou, M, Chasapis, C.T, Loutsidou, A.K, Bentrop, D, Lelli, M, Herrmann, T, Episkopou, V, Spyroulias, G.A. | Deposit date: | 2016-07-06 | Release date: | 2017-06-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity. J. Mol. Biol., 429, 2017
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6IGM
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![BU of 6igm by Molmil](/molmil-images/mine/6igm) | Cryo-EM Structure of Human SRCAP Complex | Descriptor: | Actin-related protein 6, Helicase SRCAP, RuvB-like 1, ... | Authors: | Feng, Y, Tian, Y, Wu, Z, Xu, Y. | Deposit date: | 2018-09-25 | Release date: | 2019-07-24 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of human SRCAP complex. Cell Res., 28, 2018
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8CNH
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6UQT
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8COJ
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8COT
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6YKF
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![BU of 6ykf by Molmil](/molmil-images/mine/6ykf) | VcaM4I restriction endonuclease in the presence of 5mC-modified ssDNA | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*AP*(5CM)P*AP*G)-3'), GLYCEROL, ... | Authors: | Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M. | Deposit date: | 2020-04-06 | Release date: | 2020-12-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA. Nucleic Acids Res., 49, 2021
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8P1P
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![BU of 8p1p by Molmil](/molmil-images/mine/8p1p) | USP28 in complex with AZ1 | Descriptor: | 2-[[5-bromanyl-2-[[4-fluoranyl-3-(trifluoromethyl)phenyl]methoxy]phenyl]methylamino]ethanol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Sauer, F, Karal-Nair, R, Kisker, C. | Deposit date: | 2023-05-12 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | USP28 in complex with AZ1 To Be Published
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6YEX
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![BU of 6yex by Molmil](/molmil-images/mine/6yex) | VcaM4I restriction endonuclease in the absence of DNA | Descriptor: | CHLORIDE ION, HNH endonuclease, SULFATE ION | Authors: | Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M. | Deposit date: | 2020-03-25 | Release date: | 2020-12-16 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA. Nucleic Acids Res., 49, 2021
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6YHW
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![BU of 6yhw by Molmil](/molmil-images/mine/6yhw) | Co-crystals in the P212121 space group, of a beta-cyclodextrin spacered by triazole heptyl from alpha-D-mannose, with FimH lectin at 2.00 A resolution. | Descriptor: | 2H-1,2,3-TRIAZOL-4-YLMETHANOL, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), FimH, ... | Authors: | de Ruyck, J, Bouckaert, J. | Deposit date: | 2020-03-31 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.962 Å) | Cite: | The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut. Chembiochem, 17, 2016
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8T6R
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6UQU
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