6S83
Crystal structure of methionine adenosyltransferase from Pyrococcus furiosus in complex with AMPPCP, SAM, and PCP
Summary for 6S83
| Entry DOI | 10.2210/pdb6s83/pdb |
| Related | 6S81 |
| Descriptor | S-adenosylmethionine synthase, METHYLENEDIPHOSPHONIC ACID, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | s-adenosyl methionine synthesis, cofactor biosynthesis, transferase, cytoplasmic |
| Biological source | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
| Total number of polymer chains | 8 |
| Total formula weight | 359501.17 |
| Authors | Degano, M.,Minici, C.,Porcelli, M. (deposition date: 2019-07-08, release date: 2020-02-05, Last modification date: 2024-01-24) |
| Primary citation | Minici, C.,Mosca, L.,Ilisso, C.P.,Cacciapuoti, G.,Porcelli, M.,Degano, M. Structures of catalytic cycle intermediates of the Pyrococcus furiosus methionine adenosyltransferase demonstrate negative cooperativity in the archaeal orthologues. J.Struct.Biol., 210:107462-107462, 2020 Cited by PubMed: 31962159DOI: 10.1016/j.jsb.2020.107462 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.336 Å) |
Structure validation
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