4K9J
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![BU of 4k9j by Molmil](/molmil-images/mine/4k9j) | Structure of Re(CO)3(4,7-dimethyl-phen)(Thr126His)(Lys122Trp)(His83Glu)(Trp48Phe)(Tyr72Phe)(Tyr108Phe)AzCu(II), a Rhenium modified Azurin mutant | Descriptor: | (1,10 PHENANTHROLINE)-(TRI-CARBON MONOXIDE) RHENIUM (I), Azurin, COPPER (II) ION | Authors: | Takematsu, K, Williamson, H.R, Blanco-Rodriguez, A.M, Sokolova, L, Nikolovski, P, Kaiser, J.T, Towrie, M, Clark, I.P, Vlcek Jr, A, Winkler, J.R, Gray, H.B. | Deposit date: | 2013-04-20 | Release date: | 2013-10-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Tryptophan-accelerated electron flow across a protein-protein interface. J.Am.Chem.Soc., 135, 2013
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6WSJ
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4K9Q
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6DKS
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![BU of 6dks by Molmil](/molmil-images/mine/6dks) | Structure of the Rbpj-SHARP-DNA Repressor Complex | Descriptor: | DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | Authors: | Kovall, R.A, VanderWielen, B.D, Yuan, Z. | Deposit date: | 2018-05-30 | Release date: | 2019-01-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site. Cell Rep, 26, 2019
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7C3E
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![BU of 7c3e by Molmil](/molmil-images/mine/7c3e) | Crystal structure of R97A/R150A/R203A mutant of AofleA from Arthrobotrys oligospora | Descriptor: | AofleA, GLYCEROL, SULFATE ION | Authors: | Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M. | Deposit date: | 2020-05-12 | Release date: | 2020-07-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.183 Å) | Cite: | Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora. Int.J.Biol.Macromol., 164, 2020
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4KCI
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![BU of 4kci by Molmil](/molmil-images/mine/4kci) | Structure of neuronal nitric oxide synthase heme domain in complex with N,N'-(ethane-1,2-diylbis(3,1-phenylene))bis(thiophene-2-carboximidamide) | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N,N'-(ethane-1,2-diyldibenzene-3,1-diyl)dithiophene-2-carboximidamide, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2013-04-24 | Release date: | 2014-02-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Potent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma. J.Med.Chem., 57, 2014
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7C8B
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![BU of 7c8b by Molmil](/molmil-images/mine/7c8b) | Crystal structure of the SARS-CoV-2 main protease in complex with Z-VAD(OMe)-FMK | Descriptor: | 3C-like proteinase, CHLORIDE ION, Z-VAD(OMe)-FMK | Authors: | Zeng, R, Qiao, J.X, Wang, Y.F, Li, Y.S, Yao, R, Yang, S.Y, Lei, J. | Deposit date: | 2020-05-29 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the SARS-CoV-2 main protease in complex with Z-VAD(OMe)-FMK To Be Published
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4KEJ
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4KG8
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![BU of 4kg8 by Molmil](/molmil-images/mine/4kg8) | Crystal structure of light mutant | Descriptor: | Tumor necrosis factor ligand superfamily member 14 | Authors: | Liu, W, Zhan, C, Kumar, P.R, Bonanno, J.B, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2013-04-28 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly. Structure, 22, 2014
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7CCJ
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![BU of 7ccj by Molmil](/molmil-images/mine/7ccj) | Sulfur binding domain of SprMcrA complexed with phosphorothioated DNA | Descriptor: | DNA (5'-D(*GP*GP*AP*TP*CP*AP*TP*C)-3'), HNHc domain-containing protein | Authors: | Yu, H, Zhao, G, Gan, J, Liu, G, Wu, G, He, X. | Deposit date: | 2020-06-17 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses. Nucleic Acids Res., 48, 2020
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7CCD
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![BU of 7ccd by Molmil](/molmil-images/mine/7ccd) | Sulfur binding domain of SprMcrA complexed with phosphorothioated DNA | Descriptor: | DNA (5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*GP*AS*AP*CP*GP*TP*G)-3'), HNHc domain-containing protein | Authors: | Yu, H, Li, J, Liu, G, Zhao, G, Wang, Y, Hu, W, Deng, Z, Gan, J, Zhao, Y, He, X. | Deposit date: | 2020-06-16 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses. Nucleic Acids Res., 48, 2020
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4KP4
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![BU of 4kp4 by Molmil](/molmil-images/mine/4kp4) | Deciphering cis-trans directionality and visualizing autophosphorylation in histidine kinases. | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Osmolarity sensor protein EnvZ, ... | Authors: | Casino, P, Miguel-Romero, L, Marina, A. | Deposit date: | 2013-05-13 | Release date: | 2014-02-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Visualizing autophosphorylation in histidine kinases. Nat Commun, 5, 2014
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7CHC
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6D67
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![BU of 6d67 by Molmil](/molmil-images/mine/6d67) | Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion (maltose bound form) in complex with the designed AR protein mbp3_16 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Designed AR protein mbp3_16, ... | Authors: | Gumpena, R, Lountos, G.T, Waugh, D.S. | Deposit date: | 2018-04-20 | Release date: | 2018-09-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
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4K4C
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![BU of 4k4c by Molmil](/molmil-images/mine/4k4c) | X-ray crystal structure of E. coli YbdB complexed with phenacyl-CoA | Descriptor: | Proofreading thioesterase EntH, phenacyl coenzyme A | Authors: | Ru, W, Farelli, J.D, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2013-04-12 | Release date: | 2014-07-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure and Catalysis in the Escherichia coli Hotdog-fold Thioesterase Paralogs YdiI and YbdB. Biochemistry, 53, 2014
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4KRD
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![BU of 4krd by Molmil](/molmil-images/mine/4krd) | Crystal Structure of Pho85-Pcl10 Complex | Descriptor: | Cyclin-dependent protein kinase PHO85, PHO85 cyclin-10 | Authors: | Quiocho, F.A, Zheng, F. | Deposit date: | 2013-05-16 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition. J.Biol.Chem., 288, 2013
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4KT0
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![BU of 4kt0 by Molmil](/molmil-images/mine/4kt0) | Crystal structure of a virus like photosystem I from the cyanobacterium Synechocystis PCC 6803 | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | Authors: | Mazor, Y, Nataf, D, Toporik, H, Nelson, N. | Deposit date: | 2013-05-19 | Release date: | 2014-02-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of virus-like photosystem I complexes from the mesophilic cyanobacterium Synechocystis PCC 6803. Elife, 3, 2014
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4K9O
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7CRZ
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![BU of 7crz by Molmil](/molmil-images/mine/7crz) | Crystal structure of human glucose transporter GLUT3 bound with C3361 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Solute carrier family 2, ... | Authors: | Yuan, Y.Y, Zhang, S, Wang, N, Jiang, X, Yan, N. | Deposit date: | 2020-08-14 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc.Natl.Acad.Sci.USA, 118, 2021
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7CBY
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![BU of 7cby by Molmil](/molmil-images/mine/7cby) | Structure of FOXG1 DNA binding domain bound to DBE2 DNA site | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), ... | Authors: | Dai, S.Y, Li, J, Chen, Y.H. | Deposit date: | 2020-06-15 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.646 Å) | Cite: | Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations. J.Mol.Biol., 432, 2020
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7CH5
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7CM3
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![BU of 7cm3 by Molmil](/molmil-images/mine/7cm3) | Cryo-EM structure of human NALCN in complex with FAM155A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wu, J, Yan, Z, Ke, M. | Deposit date: | 2020-07-24 | Release date: | 2020-11-11 | Last modified: | 2020-12-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the human sodium leak channel NALCN in complex with FAM155A. Nat Commun, 11, 2020
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7CNA
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![BU of 7cna by Molmil](/molmil-images/mine/7cna) | Crystal structure of Spindlin1/C11orf84 complex bound to histone H3K4me3K9me3 peptide | Descriptor: | ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-M3L-SER-GLY, ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-M3L-SER-THR, BENZAMIDINE, ... | Authors: | Qian, C.M. | Deposit date: | 2020-07-30 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation. Nat Commun, 12, 2021
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7CTQ
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![BU of 7ctq by Molmil](/molmil-images/mine/7ctq) | Peptidyl tryptophan dihydroxylase QhpG essential for tryptophylquinone cofactor biogenesis | Descriptor: | (2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(2~{R},3~{S},4~{R},5~{R},6~{R})-6-(cyclohexylmethoxy)-2-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol, FLAVIN-ADENINE DINUCLEOTIDE, HEXANE-1,6-DIOL, ... | Authors: | Oozeki, T, Nakai, T, Okajima, T. | Deposit date: | 2020-08-20 | Release date: | 2021-02-17 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.978 Å) | Cite: | Functional and structural characterization of a flavoprotein monooxygenase essential for biogenesis of tryptophylquinone cofactor. Nat Commun, 12, 2021
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6DY3
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![BU of 6dy3 by Molmil](/molmil-images/mine/6dy3) | Caenorhabditis elegans N-acylethanolamine-hydrolyzing acid amidase (NAAA) ortholog | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, N-acylethanolamine-hydrolyzing acid amidase alpha-subunit, N-acylethanolamine-hydrolyzing acid amidase beta-subunit | Authors: | Gorelik, A, Gebai, A, Illes, K, Piomelli, D, Nagar, B. | Deposit date: | 2018-07-01 | Release date: | 2018-09-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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