4KG8
Crystal structure of light mutant
Summary for 4KG8
Entry DOI | 10.2210/pdb4kg8/pdb |
Related | 3K51 3MHD 3MI8 4EN0 4FHQ 4J6G |
Descriptor | Tumor necrosis factor ligand superfamily member 14 (2 entities in total) |
Functional Keywords | structural genomics, psi-biology, new york structural genomics research consortium, nysgrc, immunity, tnf superfamily, hvem, dcr3, n-glycosylation, membrane, secreted protein, cytokine, atoms-to-animals: the immune function network, jelly-roll fold, bind tnf receptor hvem and ltbr, ltbr, protein structure initiative, ifn |
Biological source | Homo sapiens (human) |
Cellular location | Tumor necrosis factor ligand superfamily member 14, membrane form: Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor ligand superfamily member 14, soluble form: Secreted. Isoform 2: Cytoplasm: O43557 |
Total number of polymer chains | 3 |
Total formula weight | 51625.31 |
Authors | Liu, W.,Zhan, C.,Kumar, P.R.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC),Atoms-to-Animals: The Immune Function Network (IFN) (deposition date: 2013-04-28, release date: 2013-08-07, Last modification date: 2023-09-20) |
Primary citation | Liu, W.,Zhan, C.,Cheng, H.,Kumar, P.R.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C. Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly. Structure, 22:1252-1262, 2014 Cited by PubMed: 25087510DOI: 10.1016/j.str.2014.06.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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