7CBY
Structure of FOXG1 DNA binding domain bound to DBE2 DNA site
Summary for 7CBY
Entry DOI | 10.2210/pdb7cby/pdb |
Descriptor | DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), Forkhead box protein G1, ... (5 entities in total) |
Functional Keywords | foxg1, forkhead box, transcription factors, foxg1 syndrome, dbe2, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 22383.83 |
Authors | Dai, S.Y.,Li, J.,Chen, Y.H. (deposition date: 2020-06-15, release date: 2020-10-28, Last modification date: 2023-11-29) |
Primary citation | Dai, S.,Li, J.,Zhang, H.,Chen, X.,Guo, M.,Chen, Z.,Chen, Y. Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations. J.Mol.Biol., 432:6146-6156, 2020 Cited by PubMed: 33058871DOI: 10.1016/j.jmb.2020.10.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.646 Å) |
Structure validation
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