7CRZ

Crystal structure of human glucose transporter GLUT3 bound with C3361

Summary for 7CRZ

Entry DOI	10.2210/pdb7crz/pdb
Related	6M2L
Descriptor	Solute carrier family 2, facilitated glucose transporter member 3, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (4 entities in total)
Functional Keywords	mfs, hexose transporter, inhibitor, plasmodium falciparum, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	58946.16
Authors	Yuan, Y.Y.,Zhang, S.,Wang, N.,Jiang, X.,Yan, N. (deposition date: 2020-08-14, release date: 2021-01-13, Last modification date: 2023-11-29)
Primary citation	Huang, J.,Yuan, Y.,Zhao, N.,Pu, D.,Tang, Q.,Zhang, S.,Luo, S.,Yang, X.,Wang, N.,Xiao, Y.,Zhang, T.,Liu, Z.,Sakata-Kato, T.,Jiang, X.,Kato, N.,Yan, N.,Yin, H. Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33402433 DOI: 10.1073/pnas.2017749118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation