7CRZ

Crystal structure of human glucose transporter GLUT3 bound with C3361

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Solute carrier family 2, facilitated glucose transporter member 3	polymer	518	56474.5	1	UniProt (P11169) Pfam (PF00083)	Homo sapiens (Human)	Glucose transporter type 3,brain,GLUT-3
2	B (A)	(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol	non-polymer		332.4	1	Chemie (F00)
3	C, D, E, F, G... (A)	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	non-polymer		356.5	6	Chemie (OLC)
4	I (A)	water	water		18.0	135	Chemie (HOH)

Sequence modifications

A: 1 - 496 (UniProt: P11169)

PDB	External Database	Details
Met -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Asp -8	-	expression tag
Glu -7	-	expression tag
Val -6	-	expression tag
Asp -5	-	expression tag
Ala -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag
Thr 43	Asn 43	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	56474.5
Non-Polymers*	Number of molecules	7
	Total formula weight	2471.7
All*	Total formula weight	58946.2

*Water molecules are not included.