6D67

Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion (maltose bound form) in complex with the designed AR protein mbp3_16

Summary for 6D67

Entry DOI	10.2210/pdb6d67/pdb
Related PRD ID	PRD_900001
Descriptor	Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Designed AR protein mbp3_16, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (7 entities in total)
Functional Keywords	dual specificity phosphatase, dusp, c258s, hydrolase, mbp, maltose, darpin
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	2
Total formula weight	72620.71
Authors	Gumpena, R.,Lountos, G.T.,Waugh, D.S. (deposition date: 2018-04-20, release date: 2018-09-19, Last modification date: 2023-10-04)
Primary citation	Gumpena, R.,Lountos, G.T.,Waugh, D.S. MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74:549-557, 2018 Cited by PubMed: 30198887 DOI: 10.1107/S2053230X18009901 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation