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7C8B

Crystal structure of the SARS-CoV-2 main protease in complex with Z-VAD(OMe)-FMK

Summary for 7C8B
Entry DOI10.2210/pdb7c8b/pdb
Related7C7P
Related PRD IDPRD_002352
Descriptor3C-like proteinase, Z-VAD(OMe)-FMK, CHLORIDE ION, ... (4 entities in total)
Functional Keywordscoronavirus, protease, inhibitor, complex, viral protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains2
Total formula weight34346.93
Authors
Zeng, R.,Qiao, J.X.,Wang, Y.F.,Li, Y.S.,Yao, R.,Yang, S.Y.,Lei, J. (deposition date: 2020-05-29, release date: 2020-09-02, Last modification date: 2023-11-29)
Primary citationQiao, J.X.,Zeng, R.,Wang, Y.F.,Li, Y.S.,Yao, R.,Zhou, Y.L.,Chen, P.,Lei, J.,Yang, S.Y.
Crystal structure of the SARS-CoV-2 main protease in complex with Z-VAD(OMe)-FMK
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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