1QFW
 
 | | TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ... | | Authors: | Tegoni, M, Spinelli, S, Cambillau, C. | | Deposit date: | 1999-04-15 | | Release date: | 2000-04-26 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289, 1999
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4K0R
 | | Crystal structure of mouse Cryptochrome 1 | | Descriptor: | Cryptochrome-1 | | Authors: | Czarna, A, Wolf, E. | | Deposit date: | 2013-04-04 | | Release date: | 2013-06-26 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function.
Cell(Cambridge,Mass.), 153, 2013
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6T9L
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6DVC
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer | | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | Deposit date: | 2018-06-23 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
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6O9L
 | | Human holo-PIC in the closed state | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | | Deposit date: | 2019-03-14 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
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8GWM
 | | SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP | | Descriptor: | 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), Helicase, Non-structural protein 7, ... | | Authors: | Yan, L.M, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-17 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8Y0W
 | | dormant ribosome with eIF5A, eEF2 and SERBP1 | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Du, M, Zeng, F. | | Deposit date: | 2024-01-23 | | Release date: | 2024-02-07 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
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5LZZ
 | | Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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5LZU
 | | Structure of the mammalian ribosomal termination complex with accommodated eRF1 | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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4MBE
 | | Sac3:Sus1:Cdc31:Nup1 complex | | Descriptor: | CALCIUM ION, Cell division control protein 31, Nuclear mRNA export protein SAC3, ... | | Authors: | Jani, D, Meineke, B, Stewart, M. | | Deposit date: | 2013-08-19 | | Release date: | 2014-07-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.612 Å) | | Cite: | Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export.
Nucleic Acids Res., 42, 2014
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1K6O
 | | Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex | | Descriptor: | 5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ... | | Authors: | Mo, Y, Ho, W, Johnston, K, Marmorstein, R. | | Deposit date: | 2001-10-16 | | Release date: | 2002-01-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.
J.Mol.Biol., 314, 2001
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8Y7M
 | | FluPol-NS2 complex (local refinement) | | Descriptor: | Nuclear export protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | Authors: | Peng, Q, Sun, J.Q. | | Deposit date: | 2024-02-04 | | Release date: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | NS2 stabilizes polymerase hexamer to regulate transcription-replication switch of influenza A virus
To Be Published
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8Y7O
 | | FluPol-NS2 complex (hexamer) | | Descriptor: | Nuclear export protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | Authors: | Peng, Q, Sun, J.Q. | | Deposit date: | 2024-02-04 | | Release date: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | NS2 stabilizes polymerase hexamer to regulate transcription-replication switch of influenza A virus
To Be Published
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8Y0X
 | | Dormant ribosome with SERBP1 | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Du, M, Zeng, F. | | Deposit date: | 2024-01-23 | | Release date: | 2024-02-07 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
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6CYT
 | | HIV-1 TAR loop in complex with Tat:AFF4:P-TEFb | | Descriptor: | AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... | | Authors: | Schulze Gahmen, U, Hurley, J.H. | | Deposit date: | 2018-04-06 | | Release date: | 2018-12-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4V8Q
 | | Complex of SmpB, a tmRNA fragment and EF-Tu-GDP-Kirromycin with the 70S ribosome | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | | Authors: | Neubauer, C, Gillet, R, Kelley, A.C, Ramakrishnan, V. | | Deposit date: | 2011-12-10 | | Release date: | 2014-07-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
Science, 335, 2012
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7AJT
 | | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | | Authors: | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | | Deposit date: | 2020-09-29 | | Release date: | 2020-12-30 | | Last modified: | 2021-02-03 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
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7YCX
 | | The structure of INTAC-PEC complex | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | | Deposit date: | 2022-07-02 | | Release date: | 2023-03-15 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | Structural basis of INTAC-regulated transcription.
Protein Cell, 14, 2023
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7AJU
 | | Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | | Authors: | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | | Deposit date: | 2020-09-29 | | Release date: | 2020-12-30 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
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4D2G
 | | Crystal structure of human PCNA in complex with p15 peptide | | Descriptor: | P15, PROLIFERATING CELL NUCLEAR ANTIGEN | | Authors: | DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J. | | Deposit date: | 2014-05-09 | | Release date: | 2015-03-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
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5LZT
 | | Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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5WFK
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5LZV
 | | Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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6T59
 | | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex | | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S. | | Deposit date: | 2019-10-15 | | Release date: | 2019-11-27 | | Last modified: | 2020-01-15 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | TTC5 mediates autoregulation of tubulin via mRNA degradation.
Science, 367, 2020
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8ICU
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