9F37

Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1 and +1 positions (strain A/little yellow-shouldered bat/Guatemala/060/2010/H17N10)

Summary for 9F37

• Entry DOI: 10.2210/pdb9f37/pdb
• Related: 9F2R
• Descriptor: Polymerase acidic protein, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase catalytic subunit, ... (11 entities in total)
• Functional Keywords: rna-dependent rna polymerase, viral protein
• Biological source: Influenza A virus; More
• Total number of polymer chains: 5
• Total formula weight: 278283.07

Authors

Cusack, S.,Drncova, P. (deposition date: 2024-04-25, release date: 2024-09-18)

• Primary citation: Cusack, S.,Drncova, P.,Krischuns, T.,Naffakh, N.; High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit; Biorxiv, 2024; DOI: 10.1101/2023.11.20.567839

Experimental method

X-RAY DIFFRACTION (1.905 Å)