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6MFR
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BU of 6mfr by Molmil
Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3)
Descriptor: PHENOL, PHOSPHATE ION, Protein argonaute-2, ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-12
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MFN
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BU of 6mfn by Molmil
Human Argonaute2-miR-27a bound to HSUR1 target RNA
Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-11
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6NIT
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BU of 6nit by Molmil
Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4)
Descriptor: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-12-31
Release date:2019-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
5M9D
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BU of 5m9d by Molmil
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide
Descriptor: Regulator of Ty1 transposition protein 103, THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER
Authors:Jasnovidova, O, Kubicek, K, Stefl, R.
Deposit date:2016-11-01
Release date:2017-10-11
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Structure and dynamics of the RNAPII CTDsome with Rtt103.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7OM7
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BU of 7om7 by Molmil
Thosea asigna virus RdRP domain in complex with RNA and nucleotide UMPNPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
Authors:Ferrero, D.S, Falqui, M, Verdaguer, N.
Deposit date:2021-05-21
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Snapshots of a Non-Canonical RdRP in Action.
Viruses, 13, 2021
3OTC
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BU of 3otc by Molmil
Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native II
Descriptor: tRNA(His) guanylyltransferase
Authors:Hyde, S.J, Eckenroth, B.E, Doublie, S.
Deposit date:2010-09-11
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.
Proc.Natl.Acad.Sci.USA, 107, 2010
4Z4D
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BU of 4z4d by Molmil
Human Argonaute2 Bound to t1-G Target RNA
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4F
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BU of 4z4f by Molmil
Human Argonaute2 Bound to t1-DAP Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4H
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BU of 4z4h by Molmil
Human Argonaute2 A481T Mutant Bound to t1-A Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4I
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BU of 4z4i by Molmil
Human Argonaute2 A481T Mutant Bound to t1-G Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4C
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BU of 4z4c by Molmil
Human Argonaute2 Bound to t1-C Target RNA
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4G
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BU of 4z4g by Molmil
Human Argonaute2 Bound to t1-Inosine Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4E
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BU of 4z4e by Molmil
Human Argonaute2 Bound to t1-U Target RNA
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
6K32
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BU of 6k32 by Molmil
RdRp complex
Descriptor: 2'-O-methyladenosine 5'-(dihydrogen phosphate), 7-METHYLGUANOSINE, DIPHOSPHATE, ...
Authors:Li, X.W.
Deposit date:2019-05-16
Release date:2019-11-20
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of RdRps Within a Transcribing dsRNA Virus Provides Insights Into the Mechanisms of RNA Synthesis.
J.Mol.Biol., 432, 2020
5OMQ
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BU of 5omq by Molmil
Ternary complex of 9N DNA polymerase in the replicative state with three metal ions in the active site
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA Primer, DNA Template, ...
Authors:Betz, K, Marx, A, Diederichs, K.
Deposit date:2017-08-01
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Crystal structures of ternary complexes of archaeal B-family DNA polymerases.
PLoS ONE, 12, 2017
5OMV
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BU of 5omv by Molmil
Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, DNA primer, ...
Authors:Betz, K, Marx, A, Diederichs, K.
Deposit date:2017-08-01
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Crystal structures of ternary complexes of archaeal B-family DNA polymerases.
PLoS ONE, 12, 2017
4OI4
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BU of 4oi4 by Molmil
Protein complex of Clp1 bound to ATP and Mg2+ with Pcf11deltaN454deltaC563 of S. cerevisiae
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
8B9I
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BU of 8b9i by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8B9G
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BU of 8b9g by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
3JSB
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BU of 3jsb by Molmil
Crystal structure of the N-terminal domain of the Lymphocytic Choriomeningitis Virus L protein
Descriptor: RNA-directed RNA polymerase
Authors:Morin, B, Jamal, S, Ferron, F.P, Coutard, B, Bricogne, G, Canard, B, Vonrhein, C, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2009-09-10
Release date:2010-09-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
Plos Pathog., 6, 2010
7QDY
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BU of 7qdy by Molmil
RNA-bound human SKI complex
Descriptor: Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ...
Authors:Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E.
Deposit date:2021-12-01
Release date:2022-02-09
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism.
Mol.Cell, 82, 2022
8PJB
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BU of 8pjb by Molmil
Cryo-EM structure of MLE in complex with UUC RNA and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2023-06-23
Release date:2023-11-01
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8PJJ
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BU of 8pjj by Molmil
Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7UUC RNA
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2023-06-23
Release date:2023-11-22
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
3LLM
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BU of 3llm by Molmil
Crystal Structure Analysis of a RNA Helicase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase A, CACODYLATE ION, ...
Authors:Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-05-12
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.
J.Mol.Biol., 400, 2010
4L87
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BU of 4l87 by Molmil
Crystal structure of the human seryl-tRNA synthetase in complex with Ser-SA at 2.9 Angstrom resolution
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Xu, X, Yang, X.-L.
Deposit date:2013-06-16
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.897 Å)
Cite:Crystal Structure of Human Seryl-tRNA Synthetase and Ser-SA Complex Reveals a Molecular Lever Specific to Higher Eukaryotes.
Structure, 21, 2013

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