3OTC

Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native II

Summary for 3OTC

Entry DOI	10.2210/pdb3otc/pdb
Related	3OTB 3OTC 3OTD 3OTE
Descriptor	tRNA(His) guanylyltransferase (1 entity in total)
Functional Keywords	guanylyltransferase, polymerase-like palm domain, catalytic carboxylates, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9NWX6
Total number of polymer chains	2
Total formula weight	63257.88
Authors	Hyde, S.J.,Eckenroth, B.E.,Doublie, S. (deposition date: 2010-09-11, release date: 2010-11-17, Last modification date: 2024-02-21)
Primary citation	Hyde, S.J.,Eckenroth, B.E.,Smith, B.A.,Eberley, W.A.,Heintz, N.H.,Jackman, J.E.,Doublie, S. tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107:20305-20310, 2010 Cited by PubMed: 21059936 DOI: 10.1073/pnas.1010436107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.01 Å)

Structure validation