PDB: 523 resultsInfo pagesStatus searchChemie searchBIRD

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6SCW	SH3-subunit of chicken alpha spectrin solved by NMR Descriptor: Spectrin alpha chain, non-erythrocytic 1 isoform X11 Authors: Grohe, K, Hebrank, C, Linser, R. Deposit date: 2019-07-25 Release date: 2020-08-12 Last modified: 2024-01-31 Method: SOLUTION NMR Cite: Protein Motional Details Revealed by Complementary Structural Biology Techniques. Structure, 28, 2020
6PBC	Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, SODIUM ION Authors: Hajicek, N, Sondek, J. Deposit date: 2019-06-13 Release date: 2020-01-08 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.46 Å) Cite: Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations. Elife, 8, 2019
6RO9	Human spectrin SH3 domain D48G, E7V, K60V Descriptor: Spectrin alpha, non-erythrocytic 1 Authors: Reverter, D, Navarro, S, Ventura, S. Deposit date: 2019-05-10 Release date: 2020-06-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.814 Å) Cite: Human spectrin SH3 domain D48G, E7V, K60V To Be Published
6NMW	Crystal structure of the human Lyn SH3 domain Descriptor: Tyrosine-protein kinase Lyn Authors: Berndt, S, Gurevich, V.V, Iverson, T.M. Deposit date: 2019-01-12 Release date: 2019-04-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.199 Å) Cite: Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase. PLoS ONE, 14, 2019
6IPY	His-tagged Fyn SH3 domain R96I mutant Descriptor: Tyrosine-protein kinase Fyn Authors: Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.343 Å) Cite: Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
6IPZ	Fyn SH3 domain R96W mutant, crystallized with 18-crown-6 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn Authors: Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.576 Å) Cite: Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
6EDF	Fragment of a tyrosine-protein kinase Descriptor: FYN, GLYCEROL, UNKNOWN ATOM OR ION Authors: Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-08-09 Release date: 2018-08-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Fragment of a tyrosine-protein kinase To be Published
6A9C	Crystal Structure c-terminal SH3 domain of Myosin IB from Entamoeba histolytica bound to EhFP10(GEF) peptide. Descriptor: Peptide from Rho guanine nucleotide exchange factor, SULFATE ION, Unconventional myosin IB Authors: Gautam, G, Gourinath, S. Deposit date: 2018-07-13 Release date: 2019-06-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.98 Å) Cite: EhFP10: A FYVE family GEF interacts with myosin IB to regulate cytoskeletal dynamics during endocytosis in Entamoeba histolytica. Plos Pathog., 15, 2019
6GHM	Structure of PP1 alpha phosphatase bound to ASPP2 Descriptor: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Apoptosis-stimulating of p53 protein 2, ... Authors: Mouilleron, S, Bertran, T.M, Tapon, N, Zhou, Y. Deposit date: 2018-05-08 Release date: 2019-02-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.15 Å) Cite: ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail. Nat Commun, 10, 2019
5ZAU	Complex of the human FYN SH3 and monobody binder Descriptor: Monobody Binder, Tyrosine-protein kinase Fyn Authors: Reddy, P.P, Gulyani, A, Das, R. Deposit date: 2018-02-09 Release date: 2019-09-11 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells. Elife, 9, 2020
6C4S	Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69 Descriptor: Proto-oncogene tyrosine-protein kinase Src,cSrc SH3 Domain, ZINC ION Authors: Kall, S.L, Lavie, A. Deposit date: 2018-01-12 Release date: 2019-01-23 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase. Sci Rep, 9, 2019
6F3F	Autoinhibited Src kinase bound to ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Tyrosine-protein kinase Authors: von Raussendorf, F, Leonard, T.A. Deposit date: 2017-11-28 Release date: 2017-12-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.41795778 Å) Cite: A switch in nucleotide affinity governs activation of the Src and Tec family kinases. Sci Rep, 7, 2017
5YPR	Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor Descriptor: Disks large homolog 4, Synthesized GK inhibitor Authors: Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M. Deposit date: 2017-11-02 Release date: 2018-03-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.349 Å) Cite: Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep, 21, 2017
6B25	Crystal structure of human STAC1 Tandem SH3 Domains (288-402) Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein Authors: Wong King Yuen, S.M, Van Petegem, F. Deposit date: 2017-09-19 Release date: 2017-10-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ATV	The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions Descriptor: Adapter molecule crk, proline-rich motif in IAV-NS1 Authors: Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. Deposit date: 2017-08-29 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.751 Å) Cite: Molecular Mechanisms of Tight Binding through Fuzzy Interactions. Biophys. J., 114, 2018
6AMW	Abl1b Regulatory Module 'Activating' conformation Descriptor: Tyrosine-protein kinase ABL1 Authors: Kalodimos, C.G, Rossi, P, Saleh, T. Deposit date: 2017-08-11 Release date: 2017-09-27 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Atomic view of the energy landscape in the allosteric regulation of Abl kinase. Nat. Struct. Mol. Biol., 24, 2017
6AMV	Abl 1b Regulatory Module 'inhibiting state' Descriptor: Tyrosine-protein kinase ABL1 Authors: Kalodimos, C.G, Saleh, T, Rossi, P. Deposit date: 2017-08-11 Release date: 2017-09-27 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Atomic view of the energy landscape in the allosteric regulation of Abl kinase. Nat. Struct. Mol. Biol., 24, 2017
5OAZ	Crystal structure of the Abl-SH3 domain at pH 7.5 Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.03 Å) Cite: Crystal structure of the Abl-SH3 domain at pH 7.5 to be published
5OB2	Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12 Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12 to be published
5OB0	Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12 Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.172 Å) Cite: Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12 to be published
5OB1	Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12 Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.172 Å) Cite: Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12 to be published
5OAV	High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2017-06-23 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (0.95 Å) Cite: High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal to be published
5O2P	p130Cas SH3 domain PTP-PEST peptide chimera Descriptor: Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12 Authors: Hexnerova, R, Veverka, V. Deposit date: 2017-05-22 Release date: 2017-09-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017
5O2M	p130Cas SH3 domain Descriptor: Breast cancer anti-estrogen resistance 1 Authors: Hexnerova, R, Veverka, V. Deposit date: 2017-05-22 Release date: 2017-09-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017
5O2Q	p130Cas SH3 domain Vinculin peptide chimera Descriptor: Breast cancer anti-estrogen resistance 1,Vinculin Authors: Hexnerova, R, Veverka, V. Deposit date: 2017-05-22 Release date: 2017-09-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017

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