6ATV

The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions

Summary for 6ATV

Entry DOI	10.2210/pdb6atv/pdb
Descriptor	Adapter molecule crk, proline-rich motif in IAV-NS1 (3 entities in total)
Functional Keywords	sh3, crkii, nonstructural protein 1, influenza a virus, viral protein, protein binding-viral protein complex, protein binding/viral protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	8565.69
Authors	Shen, Q.,Zeng, D.,Zhao, B.,Li, P.,Cho, J.H. (deposition date: 2017-08-29, release date: 2018-08-08, Last modification date: 2023-10-04)
Primary citation	Shen, Q.,Shi, J.,Zeng, D.,Zhao, B.,Li, P.,Hwang, W.,Cho, J.H. Molecular Mechanisms of Tight Binding through Fuzzy Interactions. Biophys. J., 114:1313-1320, 2018 Cited by PubMed: 29590589 DOI: 10.1016/j.bpj.2018.01.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.751 Å)

Structure validation