Crystal structure of the human Lyn SH3 domain

Summary for 6NMW

DescriptorTyrosine-protein kinase Lyn (2 entities in total)
Functional Keywordslyn kinase, src family kinase, non-receptor tyrosine kinase, sh3 domain, oncoprotein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight8075.15
Berndt, S.,Gurevich, V.V.,Iverson, T.M. (deposition date: 2019-01-12, release date: 2019-04-17, Last modification date: 2019-04-24)
Primary citation
Berndt, S.,Gurevich, V.V.,Iverson, T.M.
Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase.
PLoS ONE, 14:e0215140-e0215140, 2019
PubMed: 30969999 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0215140
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18310 1.8% 11.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6nmw
no rotation
Molmil generated image of 6nmw
rotated about x axis by 90°
Molmil generated image of 6nmw
rotated about y axis by 90°