6IPZ
Fyn SH3 domain R96W mutant, crystallized with 18-crown-6
Summary for 6IPZ
Entry DOI | 10.2210/pdb6ipz/pdb |
Related | 3H0F |
Descriptor | Tyrosine-protein kinase Fyn, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE (3 entities in total) |
Functional Keywords | kinase, sh3 domain, 18-crown-6, crown ether, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 8378.20 |
Authors | Arold, S.T.,Aljedani, S.S.,Shahul Hameed, U.F. (deposition date: 2018-11-05, release date: 2018-11-28, Last modification date: 2023-11-22) |
Primary citation | Aldehaiman, A.,Momin, A.A.,Restouin, A.,Wang, L.,Shi, X.,Aljedani, S.,Opi, S.,Lugari, A.,Shahul Hameed, U.F.,Ponchon, L.,Morelli, X.,Huang, M.,Dumas, C.,Collette, Y.,Arold, S.T. Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478:1525-1545, 2021 Cited by PubMed: 33787846DOI: 10.1042/BCJ20201002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.576 Å) |
Structure validation
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