6IPZ
Fyn SH3 domain R96W mutant, crystallized with 18-crown-6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (Z) | Tyrosine-protein kinase Fyn | polymer | 70 | 7849.6 | 1 | UniProt (P06241) Pfam (PF00018) | Homo sapiens (Human) | |
| 2 | B, C (Z) | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE | non-polymer | 264.3 | 2 | Chemie (O4B) | |||
| 3 | D (Z) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
Z: 82 - 144 (UniProt: P06241)
| PDB | External Database | Details |
|---|---|---|
| Leu 75 | - | expression tag |
| Leu 76 | - | expression tag |
| Val 77 | - | expression tag |
| Pro 78 | - | expression tag |
| Arg 79 | - | expression tag |
| Gly 80 | - | expression tag |
| Ser 81 | - | expression tag |
| Trp 96 | Arg 96 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 7849.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 528.6 | |
| All* | Total formula weight | 8378.2 |
