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7Z8R
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BU of 7z8r by Molmil
CAND1-CUL1-RBX1
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-18
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
2LWJ
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BU of 2lwj by Molmil
NMR solution structure Myxoccoccus xanthus CdnL
Descriptor: Transcriptional regulator, CarD family
Authors:Jimenez, M, Padmanabhan, S, Mirassou, Y.
Deposit date:2012-08-01
Release date:2014-02-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Insights into RNA Polymerase Recognition and Essential Function of Myxococcus xanthus CdnL.
Plos One, 9, 2014
7Z8V
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BU of 7z8v by Molmil
CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-18
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7Z8T
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BU of 7z8t by Molmil
CAND1-SCF-SKP2 CAND1 engaged SCF rocked
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-18
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
2CB3
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BU of 2cb3 by Molmil
Crystal structure of peptidoglycan recognition protein-LE in complex with tracheal cytotoxin (monomeric diaminopimelic acid-type peptidoglycan)
Descriptor: GLCNAC(BETA1-4)-MURNAC(1,6-ANHYDRO)-L-ALA-GAMMA-D-GLU-MESO-A2PM-D-ALA, GLYCEROL, PEPTIDOGLYCAN-RECOGNITION PROTEIN-LE
Authors:Lim, J.-H, Kim, M.-S, Oh, B.-H.
Deposit date:2005-12-29
Release date:2006-01-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Preferential Recognition of Diaminopimelic Acid-Type Peptidoglycan by a Subset of Peptidoglycan Recognition Proteins
J.Biol.Chem., 281, 2006
7YNX
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BU of 7ynx by Molmil
Crystal structure of Pirh2 bound to poly-Ala peptide
Descriptor: RING finger and CHY zinc finger domain-containing protein 1, SODIUM ION, SULFATE ION, ...
Authors:Dong, C, Yan, X, Li, Y.
Deposit date:2022-08-01
Release date:2023-04-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recognition of an Ala-rich C-degron by the E3 ligase Pirh2.
Nat Commun, 14, 2023
6I9H
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BU of 6i9h by Molmil
Solution structure of TRIM28 RING domain
Descriptor: Transcription intermediary factor 1-beta, ZINC ION
Authors:Stevens, R.V, Esposito, D, Rittinger, K.
Deposit date:2018-11-23
Release date:2019-05-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity.
Life Sci Alliance, 2, 2019
6I9B
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BU of 6i9b by Molmil
NMR structure of the La module from human LARP4A
Descriptor: La-related protein 4
Authors:Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R.
Deposit date:2018-11-22
Release date:2019-03-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47, 2019
7ZBW
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BU of 7zbw by Molmil
CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-24
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
2M0E
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BU of 2m0e by Molmil
Solution Structure of Miz-1 zinc finger 6
Descriptor: ZINC ION, Zinc finger and BTB domain-containing protein 17
Authors:Bernard, D, Bedard, M, Bilodeau, J, Lavigne, P.
Deposit date:2012-10-24
Release date:2012-11-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Structure Note: Solution Structure of Miz-1 Zinc Fingers 5 to 7
To be Published
8HR1
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BU of 8hr1 by Molmil
Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L.
Deposit date:2022-12-14
Release date:2023-09-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
6J5S
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BU of 6j5s by Molmil
Crystal structure of human HINT1 mutant complexing with AP5A
Descriptor: BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ETHANESULFONIC ACID, Histidine triad nucleotide-binding protein 1
Authors:Wang, J, Fang, P, Guo, M.
Deposit date:2019-01-11
Release date:2019-09-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
6J1Z
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BU of 6j1z by Molmil
WWP2 semi-open conformation
Descriptor: NEDD4-like E3 ubiquitin-protein ligase WWP2
Authors:Liu, Z.H.
Deposit date:2018-12-30
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.
Nat Commun, 10, 2019
8HQY
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BU of 8hqy by Molmil
Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom
Descriptor: DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ...
Authors:Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L.
Deposit date:2022-12-14
Release date:2023-09-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
7DG5
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BU of 7dg5 by Molmil
Crystal structure of mouse Smc1-Smc3 hinge domain containing a D574Y mutation
Descriptor: Structural maintenance of chromosomes protein 1A, Structural maintenance of chromosomes protein 3
Authors:Seo, H, Noh, H, Oh, B.-H.
Deposit date:2020-11-11
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes.
Elife, 10, 2021
7K06
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BU of 7k06 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, ERI1 exoribonuclease 3, MAGNESIUM ION
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2020-09-03
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3'- 5' exoribonucleases
To Be Published
1U4Q
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BU of 1u4q by Molmil
Crystal Structure of Repeats 15, 16 and 17 of Chicken Brain Alpha Spectrin
Descriptor: Spectrin alpha chain, brain
Authors:Kusunoki, H, Minasov, G, MacDonald, R.I, Mondragon, A.
Deposit date:2004-07-26
Release date:2004-10-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Independent Movement, Dimerization and Stability of Tandem Repeats of Chicken Brain alpha-Spectrin
J.Mol.Biol., 344, 2004
5M32
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BU of 5m32 by Molmil
Human 26S proteasome in complex with Oprozomib
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H.
Deposit date:2016-10-14
Release date:2017-07-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.
Nat Commun, 8, 2017
7K07
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BU of 7k07 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, MANGANESE (II) ION
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2020-09-03
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3'- 5' exoribonucleases
To Be Published
7K05
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BU of 7k05 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2020-09-03
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
2MBH
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BU of 2mbh by Molmil
NMR structure of EKLF(22-40)/Ubiquitin Complex
Descriptor: Krueppel-like factor 1, Ubiquitin
Authors:Raiola, L, Omichinski, J.G.
Deposit date:2013-07-31
Release date:2013-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Characterization of a Noncovalent Complex between Ubiquitin and the Transactivation Domain of the Erythroid-Specific Factor EKLF.
Structure, 21, 2013
7DLV
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BU of 7dlv by Molmil
shrimp dUTPase in complex with Stl
Descriptor: CALCIUM ION, Orf20, SULFATE ION, ...
Authors:Ma, Q, Wang, F.
Deposit date:2020-11-30
Release date:2021-12-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.525 Å)
Cite:Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase.
Int.J.Biol.Macromol., 184, 2021
4DUQ
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BU of 4duq by Molmil
The Structure of Ca2+-loaded S100A2 at 1.3A resolution
Descriptor: CALCIUM ION, POLYETHYLENE GLYCOL (N=34), Protein S100-A2
Authors:Koch, M, Fritz, G.
Deposit date:2012-02-22
Release date:2012-03-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structure of Ca2+-loaded S100A2 at 1.3- angstrom resolution.
Febs J., 279, 2012
2M68
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BU of 2m68 by Molmil
NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R in complex with IGF2 (domain 11 structure only)
Descriptor: Insulin-like growth factor 2 receptor variant
Authors:Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S.
Deposit date:2013-03-27
Release date:2014-10-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
2M9Y
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BU of 2m9y by Molmil
Solution Structure of the Catalytic Domain of HHARI
Descriptor: E3 ubiquitin-protein ligase ARIH1, ZINC ION
Authors:Mercier, P, Spratt, D.E, Shaw, G.S.
Deposit date:2013-06-24
Release date:2013-11-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase.
Plos One, 8, 2013

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