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6I9B

NMR structure of the La module from human LARP4A

Summary for 6I9B
Entry DOI10.2210/pdb6i9b/pdb
NMR InformationBMRB: 27666
DescriptorLa-related protein 4 (1 entity in total)
Functional Keywordsla-related proteins, larps, pabp-binding protein, la module, rna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight20576.67
Authors
Conte, M.R.,Martino, L.,Atkinson, R.A.,Kelly, G.,Cruz-Gallardo, I.,De Tito, S.,Trotta, R. (deposition date: 2018-11-22, release date: 2019-03-13, Last modification date: 2023-06-14)
Primary citationCruz-Gallardo, I.,Martino, L.,Kelly, G.,Atkinson, R.A.,Trotta, R.,De Tito, S.,Coleman, P.,Ahdash, Z.,Gu, Y.,Bui, T.T.T.,Conte, M.R.
LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47:4272-4291, 2019
Cited by
PubMed: 30820564
DOI: 10.1093/nar/gkz144
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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