6AS8
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6ATS
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5C2L
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6AUP
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![BU of 6aup by Molmil](/molmil-images/mine/6aup) | Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox | Descriptor: | GLYCEROL, Potassium channel toxin gamma-KTx 2.2, SULFATE ION | Authors: | Gewe, M.M, Rupert, P, Strong, R.K. | Deposit date: | 2017-09-01 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
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5F48
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![BU of 5f48 by Molmil](/molmil-images/mine/5f48) | Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with coenzyme A | Descriptor: | CHLORIDE ION, COENZYME A, MAGNESIUM ION, ... | Authors: | Xu, Z, Skarina, T, Stogios, P.J, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-12-03 | Release date: | 2015-12-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes. ACS Infect Dis, 3, 2017
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8A23
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![BU of 8a23 by Molmil](/molmil-images/mine/8a23) | Crystal structure of SARS-CoV-2 nsp10/nsp16 methyltransferase in complex with TO383 | Descriptor: | (2R,3R,4S,5R)-2-[4-azanyl-5-(2-quinolin-3-ylethynyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol, 2'-O-methyltransferase nsp16, GLYCEROL, ... | Authors: | Hanigovsky, M, Krafcikova, P, Klima, M, Boura, E. | Deposit date: | 2022-06-02 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of SARS-CoV-2 nsp10/nsp16 methyltransferase in
complex with TO383 To Be Published
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6B1C
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![BU of 6b1c by Molmil](/molmil-images/mine/6b1c) | Macrophage Migration Inhibitory Factor in complex with a Naphthyridinone Inhibitor (4a) | Descriptor: | 2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one, Macrophage migration inhibitory factor, SULFATE ION | Authors: | Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. | Deposit date: | 2017-09-18 | Release date: | 2018-01-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.163 Å) | Cite: | Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor. ACS Med Chem Lett, 8, 2017
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5BXZ
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![BU of 5bxz by Molmil](/molmil-images/mine/5bxz) | H17 Bat Influenza NS1 RNA Binding Domain | Descriptor: | Non-structural protein 1 | Authors: | Kerry, P.S, Hale, B.G. | Deposit date: | 2015-06-09 | Release date: | 2015-08-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity. J.Virol., 89, 2015
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5BY1
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![BU of 5by1 by Molmil](/molmil-images/mine/5by1) | H18 Bat Influenza NS1 RNA Binding Domain | Descriptor: | DI(HYDROXYETHYL)ETHER, Non-structural protein 1, PENTAETHYLENE GLYCOL | Authors: | Kerry, P.S, Hale, B.G. | Deposit date: | 2015-06-09 | Release date: | 2015-08-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity. J.Virol., 89, 2015
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5EXS
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4X2X
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6B07
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![BU of 6b07 by Molmil](/molmil-images/mine/6b07) | Crystal structure of CfFPPS2, a lepidopteran type-II farnesyl diphosphate synthase, complexed with [1-phosphono-2-(1-propylpyridin-2-yl)ethyl]phosphonic acid (inhibitor 1d) | Descriptor: | 1,2-ETHANEDIOL, 2-(2,2-diphosphonoethyl)-1-propylpyridin-1-ium, Farnesyl diphosphate synthase, ... | Authors: | Picard, M.-E, Cusson, M, Shi, R. | Deposit date: | 2017-09-13 | Release date: | 2017-12-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural characterization of a lepidopteran type-II farnesyl diphosphate synthase from the spruce budworm, Choristoneura fumiferana: Implications for inhibitor design. Insect Biochem. Mol. Biol., 92, 2017
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5C94
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![BU of 5c94 by Molmil](/molmil-images/mine/5c94) | Infectious bronchitis virus nsp9 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Non-structural protein 9 | Authors: | Chen, C, Dou, Y, Yang, H, Su, D. | Deposit date: | 2015-06-26 | Release date: | 2016-06-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.438 Å) | Cite: | Structural basis for dimerization and RNA binding of avian infectious bronchitis virus nsp9. Protein Sci., 26, 2017
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5C9K
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5C7I
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6AYN
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6AZK
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7ZV0
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![BU of 7zv0 by Molmil](/molmil-images/mine/7zv0) | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-2'F,2'dAMP) | Descriptor: | 9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]purin-6-amine, Stimulator of interferon protein | Authors: | Klima, M, Smola, M, Boura, E. | Deposit date: | 2022-05-13 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-2'F,2'dAMP) To Be Published
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8A2X
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![BU of 8a2x by Molmil](/molmil-images/mine/8a2x) | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S)) | Descriptor: | 9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]purin-6-amine, Stimulator of interferon protein | Authors: | Klima, M, Smola, M, Boura, E. | Deposit date: | 2022-06-06 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S)) To Be Published
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4XCW
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6ATY
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7AHR
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![BU of 7ahr by Molmil](/molmil-images/mine/7ahr) | Enzyme of biosynthetic pathway | Descriptor: | 3-[(1-Carboxyvinyl)oxy]benzoic acid, Chorismate dehydratase, GLYCEROL | Authors: | Archna, A, Breithaupt, C, Stubbs, M.T. | Deposit date: | 2020-09-25 | Release date: | 2021-10-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Mechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis J.Biol.Chem., 2022
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2BZ0
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![BU of 2bz0 by Molmil](/molmil-images/mine/2bz0) | Crystal Structure of E. coli GTP cyclohydrolase II in complex with GTP analogue, GMPcPP, and Zinc | Descriptor: | GTP CYCLOHYDROLASE II, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Ren, J, Kotaka, M, Lockyer, M, Lamb, H.K, Hawkins, A.R, Stammers, D.K. | Deposit date: | 2005-08-09 | Release date: | 2005-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | GTP Cyclohydrolase II Structure and Mechanism. J.Biol.Chem., 280, 2005
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4XJ8
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5C7S
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