6AUP

Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox

Summary for 6AUP

Entry DOI	10.2210/pdb6aup/pdb
Related	6ATL 6ATN 6ATS 6ATU 6ATW 6ATY 6AU7
Descriptor	Potassium channel toxin gamma-KTx 2.2, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	knottins, cystine knot, toxins, toxin
Biological source	Mesobuthus martensii (Manchurian scorpion)
Cellular location	Secreted : P59938
Total number of polymer chains	16
Total formula weight	69062.82
Authors	Gewe, M.M.,Rupert, P.,Strong, R.K. (deposition date: 2017-09-01, release date: 2018-02-28, Last modification date: 2023-10-04)
Primary citation	Correnti, C.E.,Gewe, M.M.,Mehlin, C.,Bandaranayake, A.D.,Johnsen, W.A.,Rupert, P.B.,Brusniak, M.Y.,Clarke, M.,Burke, S.E.,De Van Der Schueren, W.,Pilat, K.,Turnbaugh, S.M.,May, D.,Watson, A.,Chan, M.K.,Bahl, C.D.,Olson, J.M.,Strong, R.K. Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25:270-278, 2018 Cited by PubMed: 29483648 DOI: 10.1038/s41594-018-0033-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation