Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6AUP

Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008200	molecular_function	ion channel inhibitor activity
A	0015459	molecular_function	potassium channel regulator activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity
B	0005576	cellular_component	extracellular region
B	0008200	molecular_function	ion channel inhibitor activity
B	0015459	molecular_function	potassium channel regulator activity
B	0035821	biological_process	modulation of process of another organism
B	0090729	molecular_function	toxin activity
B	0099106	molecular_function	ion channel regulator activity
C	0005576	cellular_component	extracellular region
C	0008200	molecular_function	ion channel inhibitor activity
C	0015459	molecular_function	potassium channel regulator activity
C	0035821	biological_process	modulation of process of another organism
C	0090729	molecular_function	toxin activity
C	0099106	molecular_function	ion channel regulator activity
D	0005576	cellular_component	extracellular region
D	0008200	molecular_function	ion channel inhibitor activity
D	0015459	molecular_function	potassium channel regulator activity
D	0035821	biological_process	modulation of process of another organism
D	0090729	molecular_function	toxin activity
D	0099106	molecular_function	ion channel regulator activity
E	0005576	cellular_component	extracellular region
E	0008200	molecular_function	ion channel inhibitor activity
E	0015459	molecular_function	potassium channel regulator activity
E	0035821	biological_process	modulation of process of another organism
E	0090729	molecular_function	toxin activity
E	0099106	molecular_function	ion channel regulator activity
F	0005576	cellular_component	extracellular region
F	0008200	molecular_function	ion channel inhibitor activity
F	0015459	molecular_function	potassium channel regulator activity
F	0035821	biological_process	modulation of process of another organism
F	0090729	molecular_function	toxin activity
F	0099106	molecular_function	ion channel regulator activity
G	0005576	cellular_component	extracellular region
G	0008200	molecular_function	ion channel inhibitor activity
G	0015459	molecular_function	potassium channel regulator activity
G	0035821	biological_process	modulation of process of another organism
G	0090729	molecular_function	toxin activity
G	0099106	molecular_function	ion channel regulator activity
H	0005576	cellular_component	extracellular region
H	0008200	molecular_function	ion channel inhibitor activity
H	0015459	molecular_function	potassium channel regulator activity
H	0035821	biological_process	modulation of process of another organism
H	0090729	molecular_function	toxin activity
H	0099106	molecular_function	ion channel regulator activity
I	0005576	cellular_component	extracellular region
I	0008200	molecular_function	ion channel inhibitor activity
I	0015459	molecular_function	potassium channel regulator activity
I	0035821	biological_process	modulation of process of another organism
I	0090729	molecular_function	toxin activity
I	0099106	molecular_function	ion channel regulator activity
J	0005576	cellular_component	extracellular region
J	0008200	molecular_function	ion channel inhibitor activity
J	0015459	molecular_function	potassium channel regulator activity
J	0035821	biological_process	modulation of process of another organism
J	0090729	molecular_function	toxin activity
J	0099106	molecular_function	ion channel regulator activity
K	0005576	cellular_component	extracellular region
K	0008200	molecular_function	ion channel inhibitor activity
K	0015459	molecular_function	potassium channel regulator activity
K	0035821	biological_process	modulation of process of another organism
K	0090729	molecular_function	toxin activity
K	0099106	molecular_function	ion channel regulator activity
L	0005576	cellular_component	extracellular region
L	0008200	molecular_function	ion channel inhibitor activity
L	0015459	molecular_function	potassium channel regulator activity
L	0035821	biological_process	modulation of process of another organism
L	0090729	molecular_function	toxin activity
L	0099106	molecular_function	ion channel regulator activity
M	0005576	cellular_component	extracellular region
M	0008200	molecular_function	ion channel inhibitor activity
M	0015459	molecular_function	potassium channel regulator activity
M	0035821	biological_process	modulation of process of another organism
M	0090729	molecular_function	toxin activity
M	0099106	molecular_function	ion channel regulator activity
N	0005576	cellular_component	extracellular region
N	0008200	molecular_function	ion channel inhibitor activity
N	0015459	molecular_function	potassium channel regulator activity
N	0035821	biological_process	modulation of process of another organism
N	0090729	molecular_function	toxin activity
N	0099106	molecular_function	ion channel regulator activity
O	0005576	cellular_component	extracellular region
O	0008200	molecular_function	ion channel inhibitor activity
O	0015459	molecular_function	potassium channel regulator activity
O	0035821	biological_process	modulation of process of another organism
O	0090729	molecular_function	toxin activity
O	0099106	molecular_function	ion channel regulator activity
P	0005576	cellular_component	extracellular region
P	0008200	molecular_function	ion channel inhibitor activity
P	0015459	molecular_function	potassium channel regulator activity
P	0035821	biological_process	modulation of process of another organism
P	0090729	molecular_function	toxin activity
P	0099106	molecular_function	ion channel regulator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 101

Chain	Residue
A	TYR11
A	GLN12
B	TYR11
C	TYR11
F	TYR11
F	GLN12

site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 102

Chain	Residue
B	ASP4
B	LYS6
B	HOH212
H	VAL29
A	ALA9
A	SER10
A	ARG27

site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 B 101

Chain	Residue
B	GLY-1
B	ARG1
B	LYS23
B	HOH204
G	ARG1
J	GLY-1
O	ARG1

site_id	AC4
Number of Residues	5
Details	binding site for residue SO4 B 102

Chain	Residue
B	ALA9
B	SER10
F	ILE5
F	LYS6
F	HOH203

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 C 101

Chain	Residue
C	GLY-1
C	LYS23
C	HOH213
E	PHE21
N	ARG1

site_id	AC6
Number of Residues	7
Details	binding site for residue SO4 C 102

Chain	Residue
A	LYS6
C	ALA9
C	SER10
C	ARG27
C	HOH202
L	ASP4
P	GOL101

site_id	AC7
Number of Residues	6
Details	binding site for residue SO4 F 101

Chain	Residue
C	ILE5
C	LYS6
C	HOH208
F	ALA9
F	SER10
F	ARG27

site_id	AC8
Number of Residues	12
Details	binding site for residue SO4 D 101

Chain	Residue
D	ALA9
D	SER10
D	HOH204
D	HOH206
E	ASP4
E	ILE5
E	LYS6
E	HOH205
E	HOH209
E	HOH212
E	HOH215
P	ARG27

site_id	AC9
Number of Residues	7
Details	binding site for residue SO4 D 102

Chain	Residue
D	TYR11
D	GLN12
D	HOH205
E	TYR11
G	TYR11
H	TYR11
H	GLN12

site_id	AD1
Number of Residues	7
Details	binding site for residue SO4 E 101

Chain	Residue
C	ARG1
E	GLY-1
E	ARG1
E	LYS23
K	ARG1
N	GLY-1
N	LYS23

site_id	AD2
Number of Residues	8
Details	binding site for residue SO4 E 102

Chain	Residue
E	LYS6
E	HOH201
E	HOH204
E	HOH205
J	ALA9
J	SER10
L	LYS6
P	ASN30

site_id	AD3
Number of Residues	6
Details	binding site for residue SO4 E 103

Chain	Residue
E	SER10
E	HOH213
E	HOH217
H	ILE5
H	LYS6
H	HOH203

site_id	AD4
Number of Residues	8
Details	binding site for residue GOL E 104

Chain	Residue
D	ASN25
D	ARG27
D	HOH214
E	THR3
E	ASP4
E	ARG20
P	GLY-1
P	SER0

site_id	AD5
Number of Residues	8
Details	binding site for residue SO4 G 101

Chain	Residue
B	PHE21
G	GLY-1
G	ARG1
G	LYS23
G	HOH208
G	HOH209
G	HOH212
J	ARG1

site_id	AD6
Number of Residues	4
Details	binding site for residue GOL G 102

Chain	Residue
G	SER8
G	SER10
G	HOH207
K	LYS6

site_id	AD7
Number of Residues	4
Details	binding site for residue SO4 H 101

Chain	Residue
G	LYS6
H	ALA9
H	SER10
H	HOH211

site_id	AD8
Number of Residues	6
Details	binding site for residue SO4 I 101

Chain	Residue
I	TYR11
I	GLN12
J	TYR11
K	TYR11
L	TYR11
L	GLN12

site_id	AD9
Number of Residues	6
Details	binding site for residue SO4 I 102

Chain	Residue
H	HOH201
I	ALA9
I	SER10
I	ARG27
J	LYS6
J	HOH207

site_id	AE1
Number of Residues	6
Details	binding site for residue SO4 J 101

Chain	Residue
B	ARG1
B	HOH204
J	ARG1
J	PHE21
O	GLY-1
O	LYS23

site_id	AE2
Number of Residues	5
Details	binding site for residue GOL K 101

Chain	Residue
I	LYS6
I	HOH206
K	ALA9
K	SER10
P	ASP4

site_id	AE3
Number of Residues	7
Details	binding site for residue GOL K 102

Chain	Residue
D	LYS6
K	ASP4
K	ILE5
K	LYS6
K	HOH201
L	SER10
L	ARG27

site_id	AE4
Number of Residues	5
Details	binding site for residue SO4 M 101

Chain	Residue
M	ALA9
M	SER10
N	ILE5
N	LYS6
N	HOH203

site_id	AE5
Number of Residues	5
Details	binding site for residue SO4 N 101

Chain	Residue
E	ARG1
K	GLY-1
K	LYS23
N	ARG1
N	PHE21

site_id	AE6
Number of Residues	5
Details	binding site for residue SO4 N 102

Chain	Residue
B	LYS6
H	ASN30
N	ALA9
N	SER10
N	HOH204

site_id	AE7
Number of Residues	6
Details	binding site for residue SO4 O 101

Chain	Residue
M	TYR11
M	GLN12
N	TYR11
O	TYR11
P	TYR11
P	GLN12

site_id	AE8
Number of Residues	6
Details	binding site for residue SO4 O 102

Chain	Residue
M	ILE5
M	LYS6
M	HOH204
O	ALA9
O	SER10
O	ARG27

site_id	AE9
Number of Residues	7
Details	binding site for residue GOL P 101

Chain	Residue
C	SO4102
D	ASN30
O	LYS6
O	HOH207
P	ALA9
P	SER10
P	HOH205

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)